Title

Exercise Can Prevent and Even Reverse Adverse Effects of Androgen Suppression Treatment in Men with Prostate Cancer

Document Type

Journal Article

Publisher

Nature Publishing Group

Faculty

Computing, Health and Science

School

Exercise, Biomedical and Health Science, Centre for Exercise and Sports Science Research

RAS ID

3987

Comments

This article was originally published as: Galvao, D. A., Taaffe, D., Spry, N., & Newton, R. (2007). Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer. Prostate Cancer and Prostatic Diseases , 10(4), 340-346. Original article available here

Abstract

Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects during and following therapy. In this review, we discuss common morphological and physiological ADT-related side effects or ‘Androgen Deprivation and Sarcopenia-Related Disorders’ and the existing clinical trials incorporating physical exercise in prostate cancer patients receiving active therapy. Further, training concepts and guidelines are provided for prescribing resistance exercise programs for this population.

 

Link to publisher version (DOI)

10.1038/sj.pcan.4500975