Title
Frontotemporale Lobardegenerationen, Teil 1: Diagnose und Therapie
Document Type
Journal Article
Publisher
Georg Thieme Verlag
Faculty
Computing, Health and Science
School
Exercise, Biomedical and Health Science, Centre for Alzheimer's Disease
RAS ID
7630
Abstract
Frontotemporal Lobar Degeneration (FTLD) is clinically heterogeneous, less common than Alzheimer's disease (AD), and - if at all - usually diagnosed in the presenium. The most common form, frontotemporal dementia (FTD) is characterized by changes in behaviour and personality, the less common progressive aphasia (PA) by a non-fluent aphasia and semantic dementia (SD) primarily by a loss of vocabulary and concepts. The diagnosis can be very difficult to make and therefore usually made only several years after the occurrence of the first ambiguous symptoms. The diagnosis relies on clinical criteria, including a neuropsychological collection of executive and language skills. Current therapeutic interventions aim at treating the symptomology, as no cure currently exists. Very important is the guidance and support of family members especially in patients with FTD, which are often exposed to an even greater burden than the relatives of patients with AD.

Comments
This article was originally published as: Danek, A., Diehl-Schmid, J., Grimmer, T., Laws, S. , Neumann, M., Perneczky, R., Riemenschneider, M., Kurz, A., & Forstl, H. (2009). Frontotemporale Lobardegenerationen, Teil 1: diagnose und therapie. Fortschritte der Neurologie-Psychiatrie, 77(3), 169-76. Original article available here