Document Type

Journal Article

Publisher

Frontiers Research Foundation

School

Exercise Medicine Research Institute

RAS ID

20097

Funders

ARC, Australian Research Council

Comments

Originally published as: Cormie, P., Nowak, A.K., Chambers, S.K., Galvão, D.A., Newton, R.U. (2015). The potential role of exercise in neuro-oncology in Frontiers in Oncology, (5), pp. 85. Available here.

Abstract

Patients with brain and other central nervous system cancers experience debilitating physical, cognitive, and emotional effects, which significantly compromise quality of life. Few efficacious pharmacological strategies or supportive care interventions exist to ameliorate these sequelae and patients report high levels of unmet needs in these areas. There is strong theoretical rationale to suggest exercise may be an effective intervention to aid in the management of neuro-oncological disorders. Clinical research has established the efficacy of appropriate exercise in counteracting physical impairments such as fatigue and functional decline, cognitive impairment, as well as psychological effects including depression and anxiety. While there is promise for exercise to enhance physical and psychosocial wellbeing of patients diagnosed with neurologic malignancies, these patients have unique needs and research is urgently required to explore optimal exercise prescription specific to these patients to maximize safety and efficacy. This perspective article is a discussion of potential rehabilitative effects of targeted exercise programs for patients with brain and other central nervous system cancers and highlights future research directions.

DOI

10.3389/fonc.2015.00085

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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