Title

Association of ideal cardiovascular health and brachial-ankle pulse wave velocity : A cross-sectional study in Northern China

Document Type

Journal Article

Publisher

W.B. Saunders Co.

Place of Publication

United States

Faculty

Faculty of Health, Engineering and Science

School

School of Engineering

RAS ID

19926

Comments

Originally published as: Yan, N., Zhou, Y., Wang, Youxin., Wang, A., Yang, X., Russell, A., Wu, S., ... Wang, W. (2016). Association of ideal cardiovascular health and brachial-ankle pulse wave velocity : A cross-sectional study in Northern China. Journal of Stroke and Cerebrovascular Diseases, 25(1), 41-48. doi: 10.1016/j.jstrokecerebrovasdis.2015.08.031. Original article available here

Abstract

Background Brachial–ankle pulse wave velocity (baPWV) is an index for evaluating arterial stiffness and is recognized as an independent predictor of an impending cardiovascular event. Limited large-scale population data are available regarding the relationship between baPWV and the change in ideal cardiovascular health (CVH) status, particularly among Asians. Methods A random sample of 5199 participants (≥40 years of age; 40% women) was enrolled in a cross-sectional study in China to examine the association between ideal CVH and baPWV. Arterial stiffness was defined as a baPWV of 1400 cm/second or higher. Information on CVH was collected based on the American Heart Association's CVH definition by measuring all 7 components (nonsmoking status, body mass index, physical activity, healthy diet, normal total cholesterol, blood pressure, and fasting blood glucose), with 1 or 0 for each component, and a score from 0 to 7 for each participant. Results A significant and inverse association was found between the ideal CVH score and baPWV (P <.001). The adjusted odds ratios for arterial stiffness prevalence were .17 (95% confidence interval [CI], .11-.26), .26 (95% CI, .19-.35), .42 (95% CI, .32-.52), .54 (95% CI, .42-.69), and .69 (95% CI, .54-.89) for those with CVH scores of 7-6, 5, 4, 3, and 2, respectively, compared with those with a CVH score of 1-0 (P <.001). Similarly graded relationships were observed in different age and gender subgroups (P <.001). Conclusion The favorable score of ideal CVH was inversely related to baPWV in Chinese adults, supporting the use of ideal CVH metrics as a useful tool for public health efforts.

DOI

10.1016/j.jstrokecerebrovasdis.2015.08.031