Title

Curcumin and cognition: a randomized, placebo-controlled, double-blind study of community-dwelling older adults

Document Type

Journal Article

Publisher

Cambridge University Press

School

School of Medical and Health Sciences/Centre of Excellence for Alzheimer's Disease Research and Care

RAS ID

21242

Comments

Originally published as: Rainey-Smith, S. R., Brown, B. M., Sohrabi, H. R., Shah, T., Goozee, K. G., Gupta, V. B., & Martins, R. N. (2016). Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults. British Journal of Nutrition, 115(12), 2106-2113. Original article available here.

Abstract

Curcumin therapy in animals has produced positive cognitive and behavioural outcomes; results of human trials, however, have been inconsistent. In this study, we report the results of a 12-month, randomised, placebo-controlled, double-blind study that investigated the ability of a curcumin formulation to prevent cognitive decline in a population of community-dwelling older adults. Individuals (n 96) ingested either placebo or 1500 mg/d BiocurcumaxTM for 12 months. A battery of clinical and cognitive measures was administered at baseline and at the 6-month and 12-month follow-up assessments. A significant time×treatment group interaction was observed for the Montreal Cognitive Assessment (repeated-measures analysis; time×treatment; F=3·85, P

DOI

10.1017/S0007114516001203

Access Rights

Free to read Note on publisher's website as below COPYRIGHT: © The Authors 2016