Authors

Sachiyo Yoshida
Jose Martines
Joy E. Lawn
Stephen Wall
Joao Paulo Souza
Igor Rudan
Simon Cousens
Peter Aaby
Ishag Adam
Ramesh Kant Adhikari
Namasivayam Ambalavanan
Shams El Arifeen
Dhana Raj Aryal
Sk Asiruddin
Abdullah Baqui
Aluisio J.D. Barros
Christine S. Benn
Vineet Bhandari
Shinjini Bhatnagar
Sohinee Bhattacharya
Zulfiqar A. Bhutta
Robert E. Black
Hannah Blencowe
Carl Bose
Justin Brown
Christoph Buehrer
Wally Carlo
Jose Guilherme Cecatti
Po-Yin Cheung
Robert Clark
Tim Colbourn
Agustin Conde-Agudelo
Erica Corbett
Andrew E. Czeizel
Abhik Das
Louise Tina Day
Carolyn Deal
Ashok Deorari
Ugur Dilmen
Mike English
Cyril Engmann
Fabian Esamai
Caroline Fall
Donna M. Ferriero
Peter Gisore
Tabish Hazir
Rosemary D. Higgins
Caroline S.E. Homer
Dewan E. Hoque
Lorentz Irgens
Mohammad T. Islam
Joseph de Graft-Johnson
Martias Alice Joshua
William Keenan
Soofia Khatoon
Helle Kieler
Michael S. Kramer
Eve M. Lackritz
Tina Lavender
Laurensia Lawintono
Richard Luhanga
David Marsh
Douglas McMillan
Patrick J. McNamara
Ben Willem J. Mol
Elizabeth Molyneux
Gelasius K. Mukasa
Miriam Mutabazi
Luis Carlos Nacul
Margaret Nakakeeto
Indira Narayanan
Bolajoko Olusanya
David Osrin
Vinod Paul
Christian Poets
Uma M. Reddy
Mathuram Santosham
Rubayet Sayed
Natalia E. Schlabritz-Loutsevitch
Nalini Singhal
Mary Alice Smith
Peter G. Smith
Sajid Soofi
Catherine Y. Spong
Shahin Sultana
Antoinette Tshefu
Frank van Bel
Lauren Vestewig Gray
Peter Waiswa
Wei Wang, Edith Cowan UniversityFollow
Sarah L.A. Williams
Linda Wright
Anita Zaidi
Yanfeng Zhang
Nanbert Zhong
Isabel Zuniga
Rajiv Bahl

Document Type

Journal Article

Publisher

The University of Edinburgh

School

Medical and Health Sciences

Comments

This article was originally published as: Yoshida, S., Martines, J., Lawn, J. E., Wall, S., Souza, J. P., Rudan, I., ... & Ambalavanan, N. (2016). Setting research priorities to improve global newborn health and prevent stillbirths by 2025. Journal of global health, 6(1), 010508. Original article available here.

Abstract

In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025. We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts. Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour. These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed.

DOI

10.7189/jogh.06.010508

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 2.5 License.

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