Date of Award

1-1-1995

Degree Type

Thesis

Degree Name

Master of Applied Science

Faculty

Faculty of Science, Technology and Engineering

First Advisor

Dr Catherine Comiskey

Abstract

This work is primarily aimed at determining the effect that an immunisation policy Is likely to have on the incidence of Haemophllus influenzae Type B (HIB) and systematic HIB in Western Australia. There was a significant effort made to collect data pertinent to the estimation of parameter values but since HIB has only been a notifiable disease since 1992, there was a distinct lack of relevant data available. Private communication with individual’s such as Dr Jeffrey Hanna and Dr Beryl Wild resulted in practical information being obtained that was used to estimate certain parameters. The deterministic mathematical models within the thesis are extensions of existing ideas tailored to suit the needs of this thesis. Chapter one is a basic introduction to the pursuit of modelling infectious diseases with a brief description of basic epidemiology concepts. It also shows that even simple models may not deliver analytical results. Chapter two extends a model used by Angela Mclean and allows some analytical results to be obtained by first simplifying the model and then solving using standard methods to give the equilibrium distributions for the proportions of people in each state within the model

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