Title

Alzheimer's Disease: toward a quantitative biological approach in describing its natural history and underlying mechanisms

Document Type

Book Chapter

Publisher

Elsevier Inc.

School

School of Medical and Health Sciences

RAS ID

27447

Comments

Originally published as :

Masters, C. L., Gu, B., Laws, S., Lim, Y. Y., Roberts, B., Villemagne, V. L., & Beyreuther, K. (2018). Alzheimer’s Disease: Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms. In The Molecular and Cellular Basis of Neurodegenerative Diseases (pp. 57-79). Original chapter can be found here

Abstract

Alzheimer’s disease remains a major therapeutic challenge despite a massive research effort over the past two decades. Applying quantitative mechanistic approaches to understanding the quantities and rates of Aβ amyloid production, accumulation and clearance may provide novel and more rigorous insights into developing rational therapeutic strategies.

DOI

10.1016/B978-0-12-811304-2.00003-1

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