Title

High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions

Document Type

Journal Article

Publication Title

Physiology (Bethesda, Md.)

ISSN

1548-9221

Volume

34

Issue

1

First Page

56

Last Page

70

PubMed ID

30540234

Publisher

The American Physiological Society

School

School of Medical and Health Sciences

Comments

Originally published as:

Bishop, D. J., Botella, J., Genders, A. J., Lee, M. J., Saner, N. J., Kuang, J., ... & Granata, C. (2018). High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions. Physiology, 34(1), 56-70.

Original article available here.

Abstract

It is well established that different types of exercise can provide a powerful stimulus for mitochondrial biogenesis. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the efficacy of high-intensity exercise to promote mitochondrial biogenesis in humans. The purpose of this review is to examine current controversies in the field and to highlight some important methodological issues that need to be addressed to resolve existing conflicts.

DOI

10.1152/physiol.00038.2018

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