Title

A case study of the neuropsychological outcomes following microsurgery, conventional radiotherapy and stereotactic radiotherapy for an adults recurrent craniopharyngioma

Document Type

Journal Article

Publisher

Taylor and Francis Ltd

School

School of Psychology and Social Science

RAS ID

20240

Comments

Originally published as: Preece, D., Allan, A., & Becerra, R. (2016). A case study of the neuropsychological outcomes following microsurgery, conventional radiotherapy and stereotactic radiotherapy for an adult’s recurrent craniopharyngioma. Brain injury, 30(1), 1-8. Available here.

Abstract

Objective: To examine the neuropsychological outcomes for an adult patient, 2 years after receiving microsurgery and conventional radiotherapy for a recurrent craniopharyngioma; and the impact of a further intervention, stereotactic radiotherapy, on this level of neuropsychological functioning. Participant: JD, a 30 year old male whose recurrent craniopharyngioma had 2 years earlier been treated with two operations and conventional radiotherapy. Design: JD was assessed (using standardized clinical tests) before and after a course of stereotactic radiotherapy. Results: Prior to stereotactic radiotherapy (and 2 years after microsurgery and conventional radiotherapy) JDs IQ was intact, but considerable impairments were present in executive functioning, memory, theory of mind and processing speed. Fifteen months after stereotactic radiotherapy, all neuropsychological domains remained largely static or improved, supporting the utility of this treatment option in the neuropsychological domain. However, deficits in executive functioning, memory and processing speed remained. Conclusion: These findings suggest that, even after multiple treatments, substantial cognitive impairments can be present in an adult patient with a recurrent craniopharyngioma. This profile of deficits underlines the inadequacy of relying purely on IQ as a marker for cognitive health in this population and emphasizes the need to include neuropsychological impairments as a focus of rehabilitation with these patients. © 2016 Taylor & Francis Group, LLC.

DOI

10.3109/02699052.2015.1104552

Access Rights

Not open access