This paper presents an analysis that arose from a comprehensive review of the academic and professional literature of two areas – information security management systems (ISMS) and information resources – and their relationship with information security. It analyzes the role of ISMS in protecting an organization’s information environment and infrastructure. It has identified four key areas that strongly influence the safety of information resources: cloud computing; social media/networking; mobility; and information management/big data. Commonly referred to as ‘new forces’, these four aspects are all growing exponentially and are not easily controlled by IT. Another key finding of the paper is that organizations aiming to protect their information resources need to adapt their ISMS in an environment where these new forces have exposed them to a range of external entities and influences.