Exercise Can Prevent and Even Reverse Adverse Effects of Androgen Suppression Treatment in Men with Prostate Cancer
Document Type
Journal Article
Publisher
Nature Publishing Group
Faculty
Faculty of Computing, Health and Science
School
School of Exercise, Biomedical and Health Science / Centre for Exercise and Sports Science Research
RAS ID
3987
Abstract
Side effects accompanying androgen deprivation therapy (ADT), including sarcopenia, loss of bone mass and reduction in muscle strength, can compromise physical function, particularly in older patients. Exercise, specifically resistance training, may be an effective and cost-efficient strategy to limit or even reverse some of these adverse effects during and following therapy. In this review, we discuss common morphological and physiological ADT-related side effects or ‘Androgen Deprivation and Sarcopenia-Related Disorders’ and the existing clinical trials incorporating physical exercise in prostate cancer patients receiving active therapy. Further, training concepts and guidelines are provided for prescribing resistance exercise programs for this population.
DOI
10.1038/sj.pcan.4500975
Access Rights
free_to_read
Comments
Galvao, D. A., Taaffe, D., Spry, N., & Newton, R. (2007). Exercise can prevent and even reverse adverse effects of androgen suppression treatment in men with prostate cancer. Prostate Cancer and Prostatic Diseases , 10(4), 340-346. Available here