Effects of vitamin E supplementation on recovery from repeated bouts of resistance exercise

Document Type

Journal Article


National Strength and Conditioning Association


Faculty of Computing, Health and Science


School of Exercise, Biomedical and Health Science, Centre for Alzheimer's Disease




Avery, N. G., Kaiser, J. L., Sharman, M. J., SCHEETT, T. E., Barnes, D. M., Gomez, A. L., ... & Volek, J. S. (2003). Effects of vitamin E supplementation on recovery from repeated bouts of resistance exercise. The Journal of Strength & Conditioning Research, 17(4), 801-809.


The purpose of this study was to examine the effects of vitamin E (VE) supplementation (1200 IU/day) on recovery responses to repeated bouts of resistance exercise. Non–resistance trained men were assigned to supplement with VE (n = 9) or placebo (PL; n = 9) for 3 weeks and then perform 3 resistance exercise sessions separated by 3 days of recovery (EX-1, EX-2, and EX-3). Performance was assessed at EX-1, EX-2, and EX-3. Fasting morning blood samples and perceived muscle soreness were obtained before EX-1 and for 10 consecutive days. Muscle soreness peaked after EX-1 and gradually returned to baseline values by day 6. Lower and upper body maximal strength and explosive power were significantly (p ≤ 0.05) decreased at EX-2 and EX-3 (≈10%). Plasma malondialdehyde (MDA) was significantly elevated on days 7 and 8. There were no significant differences be- tween VE and PL in muscle soreness, performance measures, or plasma MDA. Creatine kinase (CK) area under the curve from day 1 to day 10 was significantly greater for VE because of a nearly 2-fold greater increase in CK after EX-1 in VE, compared with PL (404 ± 146 and 214 ± 179 U/L, respectively). VE supplementation was not effective at attenuating putative markers of membrane damage, oxidative stress, and performance decrements after repeated bouts of whole-body concentric/eccentric resistance exercise.

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