Title

A systematic classification of the left-sided aortic arch variants based on cadaveric studies’ prevalence: Response

Document Type

Letter to the Editor

Publication Title

Surgical and Radiologic Anatomy

Volume

44

Issue

9

First Page

1251

Last Page

1252

PubMed ID

36056238

Publisher

Springer

School

School of Medical and Health Sciences

Comments

Keet, K., Gunston, G., & Alexander, R. (2022). A systematic classification of the left-sided aortic arch variants based on cadaveric studies’ prevalence: Response. Surgical and Radiologic Anatomy, 44, 1251-1252. https://doi.org/10.1007/s00276-022-03014-6

Abstract

Dear Editor-in-Chief, Surgical and Radiologic Anatomy We read with interest the manuscript titled “A systematic classification of the left-sided aortic arch variants based on cadaveric studies’ prevalence” by K Natsis et al. published in the third issue of Surgical and Radiologic Anatomy in 2021 [4]. The authors undertook a systematic review and meta-analysis of all published cadaveric studies between 1844 and 2019 reporting variation in the branching patterns of the left-sided aortic arch. The results revealed that the standard branching pattern of three separate branches arising from the arch, namely the brachiocephalic trunk, left common carotid artery, and left subclavian artery, had a pooled prevalence of 78 % (95 % CI 72 – 84 %). All variant patterns had a combined prevalence of 22 % (95 % CI 16 – 29 %). In addition, the authors proposed a new classification system, which is based on the number and order of branches arising from the arch, and the reported prevalence of each pattern. The authors concluded that variant branching patterns were more prevalent in females (23 %) than in males (19 %), and more common in individuals of African descent. While several articles describing variant patterns in American individuals of African descent are included, only one article from Africa was included in the systematic review and meta-analysis [4].

DOI

10.1007/s00276-022-03014-6

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