Title

Maternal peanut and egg consumption during breastfeeding randomized pilot trial

Document Type

Letter to the Editor

Publication Title

Pediatric Allergy and Immunology

Volume

33

Issue

9

PubMed ID

36156821

Publisher

Wiley

School

School of Medical and Health Sciences

Funders

Telethon-Perth Children's Hospital Research Fund / The Financial Markets Foundation for Children

Comments

Palmer, D. J., Silva, D. T., & Prescott, S. L. (2022). Maternal peanut and egg consumption during breastfeeding randomized pilot trial. Pediatric Allergy and Immunology, 33(9), Article e13845. https://doi.org/10.1111/pai.13845

Abstract

To the Editor, Previous findings from our egg allergy prevention trials1, 2 demonstrated that some infants have allergic reactions, including anaphylaxis, on first introduction of egg in solid foods as early as 4 months of age. Thus, much earlier interventions are needed during critical early periods of immune development when the pathways to food sensitization and food allergy appear to be initiated. Breast milk is the ideal first complete food for infants. Previous studies have demonstrated that breast milk can provide infants with small doses of food allergens, like egg3, 4 and peanut.5 We hypothesize that a maternal diet rich in food allergens during breastfeeding will provide the infant with a regular source of food allergen in early life to enable tolerance development. The aim of this Breastfeeding and Eating Nuts and Eggs for Infant Tolerance (BENEFIT) pilot trial was to investigate whether a maternal diet rich in eggs and peanuts during breastfeeding can reduce the risk of infant egg and/or peanut sensitization and allergy.

DOI

10.1111/pai.13845

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