Consensus guidelines for sarcopenia prevention, diagnosis and management in Australia and New Zealand
Journal of Cachexia, Sarcopenia and Muscle
School of Medical and Health Sciences / Nutrition and Health Innovation Research Institute
Australian National Health and Medical Research Council Investigator / Australian Medical Research Future Fund. Grant Number: APP2005987 / NHMRC / MRFF. Grant Number: APP1199726 Deakin University / Amgen / Department of Health and Human Services (DHHS) / Norman Beischer Foundation / National Heart Foundation Future Leader Fellowship. Grant Number: 102817 / Australian Government Research Training Program / Royal Perth Hospital Career Advancement Fellowship. Grant Number: CAF 130/2020 / Western Australian Future Health and Innovation Fund / Dairy Australia / California Dairy Research Foundation / National Dairy Council / Aarhus University Hospital / Danish Dairy Research Foundation / Dutch Dairy Association / Dairy Council of California / Dairy Farmers of Canada / Centre national interprofessionnel de l'economie laitiere / University of Melbourne / Austin Hospital Medical Research Foundation / Sir Edward Dunlop Medical Research Foundation / Hospital Research Foundation
NHMRC Numbers : CRE 1102208, 2003179, APP1099173, APP1162867ARC Number : GNT1174886
Sarcopenia is an age-associated skeletal muscle condition characterized by low muscle mass, strength, and physical performance. There is no international consensus on a sarcopenia definition and no contemporaneous clinical and research guidelines specific to Australia and New Zealand. The Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) Sarcopenia Diagnosis and Management Task Force aimed to develop consensus guidelines for sarcopenia prevention, assessment, management and research, informed by evidence, consumer opinion, and expert consensus, for use by health professionals and researchers in Australia and New Zealand.
A four-phase modified Delphi process involving topic experts and informed by consumers, was undertaken between July 2020 and August 2021. Phase 1 involved a structured meeting of 29 Task Force members and a systematic literature search from which the Phase 2 online survey was developed (Qualtrics). Topic experts responded to 18 statements, using 11-point Likert scales with agreement threshold set a priori at > 80 %, and five multiple-choice questions. Statements with moderate agreement (70 % – 80 %) were revised and re-introduced in Phase 3, and statements with low agreement ( < 70 %) were rejected. In Phase 3, topic experts responded to six revised statements and three additional questions, incorporating results from a parallel Consumer Expert Delphi study. Phase 4 involved finalization of consensus statements.
Topic experts from Australia (n = 62, 92.5 %) and New Zealand (n = 5, 7.5 %) with a mean ± SD age of 45.7 ± 11.8 years participated in Phase 2; 38 (56.7 %) were women, 38 (56.7 %) were health professionals and 27 (40.3 % ) were researchers/academics. In Phase 2, 15 of 18 (83.3 %) statements on sarcopenia prevention, screening, assessment, management and future research were accepted with strong agreement. The strongest agreement related to encouraging a healthy lifestyle (100 %) and offering tailored resistance training to people with sarcopenia (92.5 %). Forty-seven experts participated in Phase 3; 5/6 (83.3 %) revised statements on prevention, assessment and management were accepted with strong agreement. A majority of experts (87.9 %) preferred the revised European Working Group for Sarcopenia in Older Persons (EWGSOP2) definition. Seventeen statements with strong agreement ( > 80 %) were confirmed by the Task Force in Phase 4.
The ANZSSFR Task Force present 17 sarcopenia management and research recommendations for use by health professionals and researchers which includes the recommendation to adopt the EWGSOP2 sarcopenia definition in Australia and New Zealand. This rigorous Delphi process that combined evidence, consumer expert opinion and topic expert consensus can inform similar initiatives in countries/regions lacking consensus on sarcopenia.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Zanker, J., Sim, M., Anderson, K., Balogun, S., Brennan‐Olsen, S. L., Dent, E., ... & Scott, D. (2023). Consensus guidelines for sarcopenia prevention, diagnosis and management in Australia and New Zealand. Journal of Cachexia, Sarcopenia and Muscle, 14(1), 142-156.