Document Type

Journal Article

Publication Title

Journal of Alzheimer's disease : JAD

Volume

90

Issue

2

First Page

599

Last Page

608

PubMed ID

36155510

Publisher

IOS Press

School

Centre for Precision Health

RAS ID

52977

Funders

National Council of Science, Technology and Technological Innovation (CONCYTEC,Per ́u) / National Fund for Scientific and Technological Development (FONDECYT, Per ́u) / Global Brain Health Institute (GBHI), University of California, San Francisco / Universidad Se ̃nor de Sip ́an, Chiclayo - Per ́u

Comments

Chino, B., Zegarra-Valdivia, J., de Frutos-Lucas, J., Paredes-Manrique, C., & Custodio, N. (2022). Impact of sociodemographic features and lifestyle on cognitive performance of Peruvian adults. Journal of Alzheimer's Disease, 90(2), 599-608. https://doi.org/10.3233/JAD-220428

Abstract

Background:

Cognitive impairment and dementia may result from a combination of modifiable and nonmodifiable risk and protective factors, such as the environment, educational attainment, time devoted to cognitively stimulating activities, and physical activity.

Objective:

This study aimed to investigate the mediating role of sociodemographic characteristics and lifestyle factors in the years of education and cognitive performance in Peruvian adults.

Methods:

This cross-sectional study included 1,478 subjects assessed by Addenbrooke’s Cognitive Examination Revised (ACE-R). Using mediation models, we evaluated the mediation role of parents’ educational level, reading time (RT), and physical activity time (PAT) in the years of education (IYE) and cognitive performance.

Results:

People who reported having lived in an urban area during their childhood are estimated to have, on average, 2.085 years more formal education than those who lived in rural areas. In addition, 49% of cognitive performance scores are explained by the mediation effect of reading and physical activity time in the IYE. This implies that higher levels of education, mediated by RT and PAT per week, are 1.596 units associated with higher scores on the ACE-R.

Conclusion:

Despite the fact that nonmodifiable factors (i.e., childhood residence area, parents’ educational level) seem to exert an effect on older adults’ cognition, their influence is mediated by other factors that are indeed modifiable (i.e., reading time, physical activity engagement). In this sense, lifestyle changes could help prevent or decrease the risk of cognitive impairment and reduce the disease’s impact on vulnerable environments in Latin American and Caribbean countries.

DOI

10.3233/JAD-220428

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

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