Document Type

Journal Article

Publication Title

Health Science Reports

Volume

7

Issue

3

Publisher

Wiley

School

School of Science

RAS ID

65011

Comments

Kyei, S., Nkansah, M., Asiedu, K., Asiamah, R., Zaabaar, E., & Afrifa-Yamoah, E. (2024). Prevalence and risk factors of vernal keratoconjunctivitis among a Ghanaian clinical cohort: A case-control study. Health Science Reports, 7(3), article e1957. https://doi.org/10.1002/hsr2.1957

Abstract

Background: Vernal Keratoconjunctivitis (VKC) has been determined to be highly prevalent in countries within the tropical climate region. However, little evidence from studies conducted within this region has been put forward to support this claim. Aim: To determine the prevalence and risk factors of VKC among a Ghanaian clinical cohort. Methods: A 3-year case-control study was conducted in a tertiary eye care institution, and medical records of patients who had been diagnosed of VKC between 2018 and 2021 were reviewed. Results: Medical records of 3800 patients were reviewed. Some (Formula presented.) cases of VKC were identified, with a population prevalence rate of (Formula presented.). Males comprised (Formula presented.) of the population with VKC, with a male-to-female ratio of (Formula presented.). The disease was more prevalent (40.8%) in children ((Formula presented.) 17 years), and the overall odds of incidence decreased by 10% for a unit increase in age. Age and sex-adjusted models revealed significant positive associations between Keratoconus [aOR = 40.760, 95% CI –5.948 to 339.937], Rhinitis [cOR = 5.183, 95% CI –2.074 to 12.022] and VKC. However, the incidence of VKC was relatively less expressive among pterygium cases [cOR = 0.315, 95% CI –0.077 to 0.846]. Conclusion: VKC is highly prevalent among children and is often associated with comorbidities of atopic origin that exacerbate the impact of the disease among this vulnerable population. It is imperative that clinicians provide holistic care for children with VKC.

DOI

10.1002/hsr2.1957

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

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