Document Type

Journal Article

Publication Title

BMJ open

Volume

12

Issue

5

First Page

e056929

PubMed ID

35568486

Publisher

BMJ Publishing Group

School

School of Nursing and Midwifery / School of Science / Centre for People, Place and Planet

RAS ID

44381

Funders

Grants-in-Aid for Early-Career Scientists (JP19K19474)

Ministry of Education, Culture, Sports, Science and Technology of Japan

Comments

Mbengo, F., Zgambo, M., Afrifa-Yamoah, E., Kalembo, F. W., Honda, T., Shimpuku, Y., & Chen, S. (2022). Protocol: Systematic review protocol of the effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth globally. BMJ Open, 12(5).

https://doi.org/10.1136/bmjopen-2021-056929

Abstract

INTRODUCTION:

Human immunodeficiency virus (HIV) prevention interventions focused at reducing risky sexual behaviours are an important strategy for preventing HIV infection among youth (15-24 years) who continue to be vulnerable to the disease. This systematic review aims to synthesise current global evidence on the effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth in the last decade.

METHODS AND ANALYSIS:

MEDLINE/PubMed, EMBASE, PsychINFO, ProQuest Central, CINAHL and Web of Science databases, ClinicalTrials.gov and the WHO International Clinical Trials Registry Platform and reference lists of included studies and systematic reviews on effectiveness of HIV prevention interventions for reducing risky sexual behaviour among youth will be searched for articles published from August 2011 to August 2021. Eligible studies will be longitudinal studies including randomised controlled trials and quasi-experimental studies that examined the effectiveness of HIV prevention interventions among youth populations (15-24 years) with risky sexual behaviour as a primary or secondary outcome. Study selection and quality assessment will be undertaken independently by three reviewers and disagreements will be resolved through consensus. Data analysis will be undertaken using RevMan software V.5.3.3. A random effects meta-analysis will be conducted to report heterogeneous data where statistical pooling is achievable. We will use I2 statistics to test for heterogeneity. Where appropriate, a funnel plot will be generated to assess publication bias. Where statistical pooling is unachievable, the findings will be reported in a narrative form, together with tables and figures to assist in data presentation if required. Reporting of the systematic review will be informed by Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

ETHICS AND DISSEMINATION:

Ethical approval is not required. Findings of the systematic review will be published in a peer-reviewed journal. The findings will be of interest to researchers, healthcare practitioners and policymakers.

PROSPERO REGISTRATION NUMBER: CRD42021271774.

DOI

10.1136/bmjopen-2021-056929

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

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