Title

High-intensity single-leg cycling improves cardiovascular disease risk factor profile

Document Type

Journal Article

Publication Title

Medicine & Science in Sports & Exercise

ISSN

1530-0315

Volume

51

Issue

11

First Page

2234

Last Page

2242

PubMed ID

31145180

Publisher

Wolters Kluwer

School

School of Medical and Health Sciences

Comments

Originally published as: Gordon, N., Abbiss, C. R., Maiorana, A. J., James, A. P., Clark, K., Marston, K. J., & Peiffer, J. J. (2019). High-intensity single-leg cycling improves cardiovascular disease risk factor profile. Medicine & Science in Sports & Exercise, 51(11), 2234-2242.

Original article available here.

Abstract

INTRODUCTION: Regular exercise can reduce the risk of developing cardiovascular disease through risk factor modification, with high-intensity exercise and more recently small muscle mass training providing alternatives to moderate-intensity exercise.

METHODS: This study randomly assigned 53 healthy middle-age adults (age, 62 ± 6 yr) to complete 24 sessions (8 wk; 3 d·wk-1) of exercise training, using either high-intensity double-leg cycling (n = 17; HITDL), high-intensity single-leg cycling (n = 18; HITSL), or moderate-intensity double-leg cycling (n = 18; MCTDL). Biomarkers of cardiovascular risk (total cholesterol, triglycerides, HDL-c, LDL-c, apo-B48, and glucose), anthropometry measures (body mass, body mass index, waist circumference, and waist-to-hip ratio), resting blood pressure, and aerobic capacity were assessed pre- and postintervention.

RESULTS: Total work completed was greater (P < 0.01) in MCTDL (5938 ± 1462 kJ) compared with the HITDL (3462 ± 1063 kJ) and HITSL (4423 ± 1875 kJ). Pre- to posttraining differences were observed for waist-to-hip ratio (0.84 ± 0.09 vs 0.83 ± 0.09; P < 0.01), resting systolic blood pressure (129 ± 11 vs 124 ± 12 mm Hg; P < 0.01), total cholesterol (5.87 ± 1.17 vs 5.55 ± 0.98 mmol·L; P < 0.01), and LDL-c (3.70 ± 1.04 vs 3.44 ± 0.84 mmol·L; P < 0.01), with no differences between conditions. In addition, aerobic capacity increased after training (22.3 ± 6.4 vs 24.9 ± 7.6 mL·kg·min; P < 0.01), with no differences between conditions.

CONCLUSION: These findings suggest that all three modes of exercise can be prescribed to achieve cardiovascular risk reduction in an aging population.

Additional Information

Not free_to_read

5/12/19 AAM requested; emailed C. Abbiss

DOI

10.1249/MSS.0000000000002053

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