Title

Refining treatment strategies for iron deficient athletes

Document Type

Journal Article

Publication Title

Sports Medicine

ISSN

01121642

Volume

50

Issue

12

First Page

2111

Last Page

2123

Publisher

Springer

School

School of Medical and Health Sciences

RAS ID

32220

Comments

McCormick, R., Sim, M., Dawson, B., & Peeling, P. (2020). Refining treatment strategies for iron deficient athletes. Sports Medicine, 50(12), 2111-2123. https://doi.org/10.1007/s40279-020-01360-2

Abstract

© 2020, Springer Nature Switzerland AG. Iron deficiency (ID) is a prevailing nutritional concern amongst the athletic population due to the increased iron demands of this group. Athletes’ ability to replenish taxed iron stores is challenging due to the low bioavailability of dietary sources, and the interaction between exercise and hepcidin, the primary iron-regulatory hormone. To date, copious research has explored the link between exercise and iron regulation, with a more recent focus on optimising iron treatment applications. Currently, oral iron supplementation is typically the first avenue of iron replacement therapy beyond nutritional intervention, for treatment of ID athletes. However, many athletes encounter associated gastrointestinal side-effects which can deter them from fulfilling a full-term oral iron treatment plan, generally resulting in sub-optimal treatment efficacy. Consequently, various strategies (e.g. dosage, composition, timing) of oral iron supplementation have been investigated with the goal of increasing fractional iron absorption, reducing gastric irritation, and ultimately improving the efficacy of oral iron therapy. This review explores the various treatment strategies pertinent to athletes and concludes a contemporary strategy of oral iron therapy entailing morning supplementation, ideally within the 30 min following morning exercise, and in athletes experiencing gut sensitivity, consumed on alternate days or at lower doses.

DOI

10.1007/s40279-020-01360-2

Research Themes

Health

Priority Areas

Exercise, nutrition, lifestyle and other interventions for optimal health across the lifespan

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