Date of Award

2001

Degree Type

Thesis

Degree Name

Bachelor of Science Honours

Faculty

Faculty of Communications, Health and Science

First Advisor

Alan Bittles

Abstract

Patterns s of genetic diversity within and between three co-resident Muslim populations from Gansu Provence in the Peoples Republic of China were examined and the results contrasted with historical information. This study of members of the Bo'an, Salar and Dongxiang communities will contribute to a clearer understanding of the origins and migratory patterns of Muslims in PR China, and more generally the effect of population subdivision on gene pool structure and composition. Ten autosomal and live Y-chromosome microsatellite loci were genotyped to determine allele distribution patterns. Subsequently, the D-loop region of mitochondrial DNA was sequenced to complement the autosomal and Y-chromosome data. To infer between- and within- population relationships, data were analysed by several alternative statistical techniques based on either the Infinite Allele Mutation model or the Stepwise Mutation model. Due to the endogamous nature of the three populations, increased levels of homozygosity at autosomal loci were observed. Y-chromosome data exhibited major differences between the study populations, whilst mitochondrial DNA suggested more consistent inter-community relationships. Demographic information was also assessed to provide a more detailed account of population structure and phylogeny.

Included in

Genetics Commons

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