Isolation and Expression Analysis of a Pax Group III Gene from the Crustacean Cherax Destructor

Authors

Robert White, Edith Cowan University
Tina M. Lamey, Edith Cowan University
Melanie Ziman, Edith Cowan UniversityFollow
Annette Koenders, Edith Cowan UniversityFollow

Document Type

Journal Article

Publisher

Springer Verlag

Faculty

Faculty of Computing, Health and Science

School

School of Exercise, Biomedical and Health Science

RAS ID

3673

Comments

White, R. B., Lamey, T. M., Ziman, M. R., & Koenders, A. E. (2005). Isolation and expression analysis of a Pax group III gene from the crustacean Cherax destructor. Development Genes and Evolution, 215(6), 306-312. Available here

Abstract

Pax genes encode transcription factors that are critical regulators of key developmental processes in evolutionarily diverse animal phyla. Here we report the first isolation of a Pax gene from a crustacean: a Pax group III gene we have termed CdpaxIII that contains highly conserved DNA-binding domains, the paired domain and homeodomain. CdpaxIII is expressed in the embryo, in adult limb muscle during both quiescence and regeneration, and during the distinct process of epimorphic limb regeneration. Interestingly, CdpaxIII is expressed as two distinct alternate transcripts, one of which is novel in lacking a large portion of its paired domain.

DOI

10.1007/s00427-005-0478-9