Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption

Document Type

Journal Article

Publisher

Human Kinetics Publishers

Faculty

Faculty of Computing, Health and Science

School

School of Exercise, Biomedical and Health Science / Centre for Exercise and Sports Science Research

RAS ID

8673

Comments

Armstrong, L. E., Pumerantz, A. C., Roti, M. W., Judelson, D. A., Watson, G., Dias, J. C., ... & Kellogg, M. (2005). Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption. International journal of sport nutrition and exercise metabolism, 15(3), 252-265.

Abstract

This investigation determined if 3 levels of controlled caffeine consumption affected fluid-electrolyte balance and renal function differently. Healthy males (mean ± standard deviation; age, 21.6 ± 3.3 y) consumed 3 mg caffeine · kg−1 · d−1 on days 1 to 6 (equilibration phase). On days 7 to 11 (treatment phase), subjects consumed either 0 mg (C0; placebo; n = 20), 3 mg (C3; n = 20), or 6 mg (C6; n = 19) caffeine · kg−1 · d−1 in capsules, with no other dietary caffeine intake. The following variables were unaffected (P > 0.05) by different caffeine doses on days 1, 3, 6, 9, and 11 and were within normal clinical ranges: body mass, urineosmolality, urine specific gravity, urine color, 24-h urine volume, 24-h Na+ and K+ excretion, 24-h creatinine, blood urea nitrogen, serum Na+ and K+, serum osmolality, hematocrit, and total plasma protein. Therefore, C0, C3, and C6 exhibited no evidence of hypohydration. These findings question the widely accepted notion that caffeine consumption acts chronically as a diuretic.

DOI

10.1123/ijsnem.15.3.252

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Link to publisher version (DOI)

10.1123/ijsnem.15.3.252