Effect of prenatal zinc supplementation on birthweight

Document Type

Journal Article

Faculty

Faculty of Computing, Health and Science

School

School of Exercise, Biomedical and Health Science

RAS ID

7745

Comments

Saaka, M., Oosthuizen, J., & Beatty, S. (2009). Effect of Prenatal Zinc Supplementation on Birthweight. Journal of Health, Population and Nutrition, 27(5), 619-631. Available here

Abstract

Although iron and zinc deficiencies are known to occur together and also appear to be high in Ghana, a few supplementation studies addressed this concurrently in pregnancy. In a double-blind, randomized controlled trial, 600 pregnant women in Ghana were randomly assigned to receive either a combined supplement of 40 mg of zinc as zinc gluconate and 40 mg of iron as ferrous sulphate or 40 mg of elemental iron as ferrous sulphate. Overall, there was no detectable difference in the mean birthweight between the study groups, although the effect of iron-zinc supplementation on the mean birthweight was masked by a strong interaction between the type of supplement and the iron status of participants [F (1,179)=5.614, p=0.019]. Prenatal iron-zinc supplementation was effective in increasing the mean birthweight among anaemic and iron-deficient women but not among women with elevated iron stores in early pregnancy.

DOI

10.3329/jhpn.v27i5.3638

Access Rights

free_to_read

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Link to publisher version (DOI)

10.3329/jhpn.v27i5.3638