Effects of transcranial direct current stimulation of the motor cortex on prefrontal cortex activation during a neuromuscular fatigue task: An fNIRS study
Document Type
Journal Article
Keywords
hemoglobin, adult, blood oxygenation, brain function, cell activation, conference paper, controlled study, deoxygenation, edurance time, flexor reflex, hemoglobin blood level, human, human experiment, male, motor cortex, muscle isometric contraction, muscle strength, muscle weakness, near infrared spectroscopy, neuromodulation, neuromuscular stimulator, normal human, prefrontal cortex, priority journal, task performance, torque integral, transcranial direct current stimulation, treatment outcome, Adult, Elbow, Fatigue, Hemoglobins, Humans, Isometric Contraction, Male, Motor Cortex, Neuromuscular Junction, Oxyhemoglobins, Prefrontal Cortex, Psychomotor Performance, Spectroscopy, Near-Infrared, Transcranial Magnetic Stimulation
Faculty
Faculty of Health, Engineering and Science
School
School of Exercise and Health Sciences
RAS ID
16810
Abstract
This study investigated whether manipulation of motor cortex excitability by transcranial direct current stimulation (tDCS) modulates neuromuscular fatigue and functional near-infrared spectroscopy (fNIRS)-derived prefrontal cortex (PFC) activation. Fifteen healthy men (27.7 ± 8.4 years) underwent anodal (2 mA, 10 min) and sham (2 mA, first 30 s only) tDCS delivered to the scalp over the right motor cortex. Subjects initially performed a baseline sustained submaximal (30 % maximal voluntary isometric contraction, MVC) isometric contraction task (SSIT) of the left elbow flexors until task failure, which was followed 50 min later by either an anodal or sham treatment condition, then a subsequent posttreatment SSIT. Endurance time (ET), torque integral (TI), and fNIRS-derived contralateral PFC oxygenated (O2Hb) and deoxygenated (HHb) hemoglobin concentration changes were determined at task failure. Results indicated that during the baseline and posttreatment SSIT, there were no significant differences in TI and ET, and increases in fNIRS-derived PFC activation at task failure were observed similarly regardless of the tDCS conditions. This suggests that the PFC neuronal activation to maintain muscle force production was not modulated by anodal tDCS.
Comments
Muthalib, M., Kan, B., Nosaka, K., & Perrey, S. (2013). Effects of transcranial direct current stimulation of the motor cortex on prefrontal cortex activation during a neuromuscular fatigue task: An fNIRS study. In S. Van Huffel, G. Naulaers, A. Caicedo, D. F. Bruley & D. K. Harrison (Eds), Oxygen transport to tissue XXXV (pp. 73-79). New York: Springer. Available here