The voices of stakeholders nvolved in precision medicine: The co-design and evaluation of qualitative indicators of intervention acceptability, fidelity and context in PRecISion medicine for children with cancer in Australia
Document Type
Journal Article
Publication Title
Qualitative Health Research
Publisher
Sage
School
School of Nursing and Midwifery
RAS ID
45449
Funders
Luminesce Alliance – Innovation for Children’s Health
National Health and Medical Research Council
Grant Number
NHMRC Numbers : APP1176620, APP1135048, APP9100002
Abstract
We report a novel approach of amalgamating implementation outcomes of acceptability and fidelity alongside context as a new way of qualitatively evaluating implementation outcomes and context of a precision medicine intervention. A rapid qualitative online proforma was co-designed with stakeholders and sent to a purposive sample of healthcare professionals involved in an early-phase clinical trial intervention. Data were analysed using Framework Analysis. A total of 24 out of 68 proformas were returned. Although some participants raised concerns about drug medication access issues, the main intervention was well accepted and understood across professional groups. Comprehension was enhanced through exposure to specialist multidisciplinary meeting arrangements. In conclusion, a rapid data collection tool and framework are now available to assess readily measurable, qualitative indicators of acceptability, fidelity of receipt and contextual fit within the dynamic precision medicine context.
DOI
10.1177/10497323221120501
Access Rights
subscription content
Comments
Smith, J., Braithwaite, J., O’Brien, T. A., Smith, S., Tyrrell, V. J., Mould, E. V., ... & Rapport, F. (2022). The voices of stakeholders nvolved in precision medicine: The co-design and evaluation of qualitative indicators of intervention acceptability, fidelity and context in PRecISion medicine for children with cancer in Australia. Qualitative Health Research, 32(12), 1865-1880.
https://doi.org/10.1177/10497323221120501