The voices of stakeholders nvolved in precision medicine: The co-design and evaluation of qualitative indicators of intervention acceptability, fidelity and context in PRecISion medicine for children with cancer in Australia
Abstract
We report a novel approach of amalgamating implementation outcomes of acceptability and fidelity alongside context as a new way of qualitatively evaluating implementation outcomes and context of a precision medicine intervention. A rapid qualitative online proforma was co-designed with stakeholders and sent to a purposive sample of healthcare professionals involved in an early-phase clinical trial intervention. Data were analysed using Framework Analysis. A total of 24 out of 68 proformas were returned. Although some participants raised concerns about drug medication access issues, the main intervention was well accepted and understood across professional groups. Comprehension was enhanced through exposure to specialist multidisciplinary meeting arrangements. In conclusion, a rapid data collection tool and framework are now available to assess readily measurable, qualitative indicators of acceptability, fidelity of receipt and contextual fit within the dynamic precision medicine context.
RAS ID
45449
Document Type
Journal Article
Date of Publication
10-1-2022
Funding Information
Luminesce Alliance – Innovation for Children’s Health
National Health and Medical Research Council
School
School of Nursing and Midwifery
Grant Number
NHMRC Numbers : APP1176620, APP1135048, APP9100002
Copyright
subscription content
Publisher
Sage
Recommended Citation
Smith, J., Braithwaite, J., O’Brien, T. A., Smith, S., Tyrrell, V. J., Mould, E. V., Long, J. C., & Rapport, F. (2022). The voices of stakeholders nvolved in precision medicine: The co-design and evaluation of qualitative indicators of intervention acceptability, fidelity and context in PRecISion medicine for children with cancer in Australia. DOI: https://doi.org/10.1177/10497323221120501
Comments
Smith, J., Braithwaite, J., O’Brien, T. A., Smith, S., Tyrrell, V. J., Mould, E. V., ... & Rapport, F. (2022). The voices of stakeholders nvolved in precision medicine: The co-design and evaluation of qualitative indicators of intervention acceptability, fidelity and context in PRecISion medicine for children with cancer in Australia. Qualitative Health Research, 32(12), 1865-1880.
https://doi.org/10.1177/10497323221120501