Document Type

Journal Article

Publication Title

Journal of Bone and Mineral Research

Volume

38

Issue

5

First Page

665

Last Page

677

PubMed ID

36795323

Publisher

Wiley

School

School of Medical and Health Sciences / Nutrition and Health Innovation Research Institute

RAS ID

54260

Funders

National Health and Medical Research Council / Australian Government / Canadian Institutes of Health Research. Grant Number: MOP-82893 / Cancer Council of Western Australia / Curtin University of Technology / Edith Cowan University / Murdoch University / Royal Perth Hospital Research Foundation. Grant Number: CAF 130/2020 / Telethon Kids Institute / The Raine Medical Research Foundation / The University of Notre Dame Australia / The University of Western Australia / Western Australian Future Health Research and Innovation Fund / Women and Infants Research Foundation

Grant Number

NHMRC Numbers : GNT1174886, 634457, 1022134, 211912, 003209, 353514

Comments

Tan, J., Ng, C. A., Hart, N. H., Rantalainen, T., Sim, M., Scott, D., ... & Chivers, P. (2023). Reduced peak bone mass in young adults with low motor competence. Journal of Bone and Mineral Research, 38(5), 665-677. https://doi.org/10.1002/jbmr.4788

Abstract

Although suboptimal bone health has been reported in children and adolescents with low motor competence (LMC), it is not known whether such deficits are present at the time of peak bone mass. We examined the impact of LMC on bone mineral density (BMD) in 1043 participants (484 females) from the Raine Cohort Study. Participants had motor competence assessed using the McCarron Assessment of Neuromuscular Development at 10, 14, and 17 years, and a whole-body dual-energy X-ray absorptiometry (DXA) scan at 20 years. Bone loading from physical activity was estimated from the International Physical Activity Questionnaire at the age of 17 years. The association between LMC and BMD was determined using general linear models that controlled for sex, age, body mass index, vitamin D status, and prior bone loading. Results indicated LMC status (present in 29.6% males and 21.9% females) was associated with a 1.8% to 2.6% decrease in BMD at all load-bearing bone sites. Assessment by sex showed that the association was mainly in males. Osteogenic potential of physical activity was associated with increased BMD dependent on sex and LMC status, with males with LMC showing a reduced effect from increasing bone loading. As such, although engagement in osteogenic physical activity is associated with BMD, other factors involved in physical activity, eg, diversity, movement quality, may also contribute to BMD differences based upon LMC status. The finding of lower peak bone mass for individuals with LMC may reflect a higher risk of osteoporosis, especially for males; however, further research is required.

DOI

10.1002/jbmr.4788

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