Document Type
Journal Article
Publication Title
Nutrients
Volume
15
Issue
12
PubMed ID
37375573
Publisher
MDPI
School
School of Medical and Health Sciences / Nutrition and Health Innovation Research Institute / School of Science
RAS ID
60220
Funders
Edith Cowan University / Australian Government Research Training Program Scholarship
Abstract
We aimed to compare the dietary intakes of Australian patients with non-alcoholic fatty liver disease (NAFLD) to general Australian population intake data and determine whether the intake of any nutrient or food group was able to predict the degree of steatosis. Dietary data from fifty adult patients with NAFLD were compared to intake data from the Australian Health Survey for energy, macronutrients, fat sub-types, alcohol, iron, folate, sugar, fibre, sodium and caffeine. Linear regression models adjusting for potential confounders (age, sex, physical activity and body mass index) were used to examine predictive relationships between hepatic steatosis (quantified via magnetic resonance spectroscopy) and dietary components. The mean percentage differences between NAFLD and Australian usual intakes were significant for energy, protein, total fat, saturated fat, monounsaturated and polyunsaturated fats (all p < 0.001). The contribution of fat and protein to total energy intake was significantly higher in the NAFLD cohort (p < 0.05). No individual nutrients or food groups were strongly related to hepatic fat in the adjusted models. Higher overall consumption appears to be a major feature of dietary intake in NAFLD when compared to the general population. A whole-diet approach to NAFLD treatment and prevention is likely to be more effective than focusing on single food components.
DOI
10.3390/nu15122669
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Properzi, C., Adams, L. A., Lo, J., Sherriff, J. L., Jeffrey, G. P., & O'Sullivan, T. A. (2023). Higher overall intakes are the defining feature of dietary intakes in NAFLD and compared to the general population. Nutrients, 15(12), article 2669. https://doi.org/10.3390/nu15122669