Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling

Authors

Jin-Soo Kim, Edith Cowan UniversityFollow
Dennis R. Taaffe, Edith Cowan UniversityFollow
Daniel A. Galvão, Edith Cowan UniversityFollow
Fred Saad, Edith Cowan UniversityFollow
Robert U. Newton, Edith Cowan UniversityFollow

Document Type

Journal Article

Publication Title

Exercise and Sport Sciences Reviews

Publisher

Wolters Kluwer

School

School of Medical and Health Sciences / Exercise Medicine Research Institute

RAS ID

60376

Comments

This is a non-final version of an article published in final form in (Kim, J. S., Taaffe, D. R., Galvão, D. A., Saad, F., & Newton, R. U. (2023). Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling. Exercise and Sport Sciences Reviews, 51(4), 161-168. https://doi.org/10.1249/JES.0000000000000323)

Kim, J. S., Taaffe, D. R., Galvão, D. A., Saad, F., & Newton, R. U. (2023). Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling. Exercise and Sport Sciences Reviews, 51(4), 161-168. https://doi.org/10.1249/JES.0000000000000323

Abstract

A prominent toxicity of androgen suppression in patients with prostate cancer (PCa) is loss of skeletal muscle. Exercise may induce tumor suppression through the endocrinal function of skeletal muscle; however, this is currently unknown. In this review, we summarize our work demonstrating the acute and chronic myokine response to exercise and the tumor-suppressive effect of circulatory milieu alteration in PCa patients. © Lippincott Williams & Wilkins.

DOI

10.1249/JES.0000000000000323