Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling

Authors/Creators

Jin-Soo Kim, Edith Cowan UniversityFollow
Dennis R. Taaffe, Edith Cowan UniversityFollow
Daniel A. Galvão, Edith Cowan UniversityFollow
Fred Saad, Edith Cowan UniversityFollow
Robert U. Newton, Edith Cowan UniversityFollow

Abstract

A prominent toxicity of androgen suppression in patients with prostate cancer (PCa) is loss of skeletal muscle. Exercise may induce tumor suppression through the endocrinal function of skeletal muscle; however, this is currently unknown. In this review, we summarize our work demonstrating the acute and chronic myokine response to exercise and the tumor-suppressive effect of circulatory milieu alteration in PCa patients. © Lippincott Williams & Wilkins.

RAS ID

60376

Document Type

Journal Article

Date of Publication

10-31-2023

School

School of Medical and Health Sciences / Exercise Medicine Research Institute

Publisher

Wolters Kluwer

Comments

This is a non-final version of an article published in final form in (Kim, J. S., Taaffe, D. R., Galvão, D. A., Saad, F., & Newton, R. U. (2023). Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling. Exercise and Sport Sciences Reviews, 51(4), 161-168. https://doi.org/10.1249/JES.0000000000000323)

Kim, J. S., Taaffe, D. R., Galvão, D. A., Saad, F., & Newton, R. U. (2023). Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling. Exercise and Sport Sciences Reviews, 51(4), 161-168. https://doi.org/10.1249/JES.0000000000000323

Recommended Citation

Kim, J., Taaffe, D. R., Galvão, D. A., Saad, F., & Newton, R. U. (2023). Exercise mediates myokine release and tumor suppression in prostate cancer independent of androgen signaling. DOI: https://doi.org/10.1249/JES.0000000000000323