Weathering the storm: Diagnosis and treatment of a life-threatening disseminated nocardia otitidiscaviarum infection

Authors

Li Yan Zhang
Liang Wang, Edith Cowan UniversityFollow
Zeeshan Umar
Yuan Hong Huang
Bing Gu

Document Type

Journal Article

Publication Title

Frontiers in Cellular and Infection Microbiology

Volume

14

Publisher

Frontiers

School

Centre for Precision Health / School of Medical and Health Sciences

RAS ID

71166

Funders

Basic and Applied Basic Research Foundation of Guangdong Province / Ganzhou Science and Technology Bureau Project

Grant Number

2021A1515220022, GZ2022ZSF252

Comments

Zhang, L. Y., Wang, L., Umar, Z., Huang, Y. H., & Gu, B. (2024). Weathering the storm: diagnosis and treatment of a life-threatening disseminated Nocardia otitidiscaviarum infection. Frontiers in Cellular and Infection Microbiology, 14, 1397847. https://doi.org/10.3389/fcimb.2024.1397847

Abstract

Nocardiosis demonstrates a temporal categorization that includes acute, subacute, and chronic stages alongside distinct typical localizations such as pulmonary, cutaneous, and disseminated forms. Disseminated nocardiosis, commonly caused by Nocardia asteroides, N. brasiliensis, and N. farcinica, continues to result in substantial morbidity and mortality. Herein, we report a life-threatening disseminated nocardiosis caused by Nocardia otitidiscaviarum in a patient with minimal change disease. This study emphasizes the difficulty in the diagnosis and treatment of unknown infections in clinical settings and highlights the important role played by laboratories in solving infectious diseases caused by rare pathogens.

DOI

10.3389/fcimb.2024.1397847

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 License.