The multidimensional sleep health of individuals with multiple sclerosis and Huntington’s disease and healthy controls
Document Type
Journal Article
Publication Title
Journal of Clinical Sleep Medicine
Volume
20
Issue
6
First Page
967
Last Page
972
PubMed ID
38305780
Publisher
The American Academy of Sleep Medicine
School
School of Medical and Health Sciences / Centre for Precision Health
Funders
Multiple Sclerosis Society of Western Australia
Grant Number
G1004557
Abstract
Study Objectives: Sleep issues are common for people with neurodegenerative conditions, yet research has focused on specific aspects of sleep. While important, a more holistic approach to investigating sleep, termed “sleep health,” considers sleep’s positive and negative aspects. Current studies exploring sleep health have lacked a control group for reference. For the first time, this study investigated the sleep health of people living with multiple sclerosis and Huntington’s disease (HD) and compared it with a community sample. Methods: 111 people, including 43 with multiple sclerosis, 19 with HD, and 49 from a community sample, participated in this study. The data, including actigraphy, Pittsburgh Sleep Quality Index, and Epworth Sleepiness Scale, were collected as part of ongoing research studies. Seven sleep health domains were determined from the collected data, and a composite sleep health score was developed. Analysis of variance and independent t tests were performed to identify population and sex differences. Results: The HD group had higher sleep regularity and lower sleep rhythmicity than the multiple sclerosis and community sample groups. The HD group had significantly less sleep duration than the multiple sclerosis group. No significant differences between the groups were observed in the sleep health composite score. Males had significantly higher sleep regularity within the HD group but significantly lower sleepiness scores in the community sample. Conclusions: These findings indicate that people with HD may experience greater variance in their wake times, therefore decreasing the consistency of being awake or asleep 24 hours apart. Understanding the mechanisms for this should be explored in people with HD.
DOI
10.5664/jcsm.11052
Access Rights
subscription content
Comments
Turner, M., Griffiths, M., Laws, M., Vial, S., Bartlett, D., & Cruickshank, T. (2024). The multidimensional sleep health of individuals with multiple sclerosis and Huntington’s disease and healthy controls. Journal of Clinical Sleep Medicine, 20(6), 967-972. https://doi.org/10.5664/jcsm.11052