Author Identifier
Kevin M. Mendez: https://orcid.org/0000-0002-8832-2607
Stacey N. Reinke: https://orcid.org/0000-0002-0758-0330
David I. Broadhurst: https://orcid.org/0000-0003-0775-9581
Document Type
Journal Article
Publication Title
Nature Communications
Volume
16
Issue
1
First Page
1700
PubMed ID
39962039
Publisher
Nature
School
School of Science
Funders
National Heart, Lung, and Blood Institute (R01HL155742)
Abstract
The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can bridge this gap by capturing the real-time dynamic relationship between underlying genetics and the environment. This perspective highlights the pivotal role of integrating EMR and post-genomics for personalized health, reflecting on lessons from past efforts, and outlining a roadmap of challenges and opportunities that must be addressed to realize the potential of precision medicine.
DOI
10.1038/s41467-025-56442-4
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
Comments
Mendez, K. M., Reinke, S. N., Kelly, R. S., Chen, Q., Su, M., McGeachie, M., ... & Lasky-Su, J. A. (2025). A roadmap to precision medicine through post-genomic electronic medical records. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56442-4