Author Identifier (ORCID)
Kevin M. Mendez: https://orcid.org/0000-0002-8832-2607
Stacey N. Reinke: https://orcid.org/0000-0002-0758-0330
David I. Broadhurst: https://orcid.org/0000-0003-0775-9581
Abstract
The promise of integrating Electronic Medical Records (EMR) and genetic data for precision medicine has largely fallen short due to its omission of environmental context over time. Post-genomic data can bridge this gap by capturing the real-time dynamic relationship between underlying genetics and the environment. This perspective highlights the pivotal role of integrating EMR and post-genomics for personalized health, reflecting on lessons from past efforts, and outlining a roadmap of challenges and opportunities that must be addressed to realize the potential of precision medicine.
Document Type
Journal Article
Date of Publication
2-17-2025
Volume
16
Issue
1
PubMed ID
39962039
Publication Title
Nature Communications
Publisher
Nature
School
School of Science
Funders
National Heart, Lung, and Blood Institute (R01HL155742)
Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.
First Page
1700
Comments
Mendez, K. M., Reinke, S. N., Kelly, R. S., Chen, Q., Su, M., McGeachie, M., ... & Lasky-Su, J. A. (2025). A roadmap to precision medicine through post-genomic electronic medical records. Nature Communications, 16(1). https://doi.org/10.1038/s41467-025-56442-4