Author Identifier
Nicolas H. Hart: https://orcid.org/0000-0003-2794-0193
Document Type
Journal Article
Publication Title
Supportive Care in Cancer
Volume
33
Issue
2
PubMed ID
39853439
Publisher
Springer
School
Exercise Medicine Research Institute / School of Medical and Health Sciences
Funders
Mazda Foundation / National Institutes of Health (R21NR020497) / National Health and Medical Research Council
Grant Number
NHMRC Numbers : APP2017080, APP1176221, APP1194051, GNT1154651
Abstract
Purpose: Cancer-related cognitive impairment (CRCI) can have a profound impact on the lives of cancer survivors. A multitude of subjective and objective assessment tools exist to assess the presence and severity of CRCI. However, no purpose-built tool exists to assess the unmet needs of cancer survivors directly relating to CRCI. This paper details the development and initial validation of the Multinational Association of Supportive Care in Cancer - Unmet Needs Assessment of Cancer-Related Cognitive Impairment Impact (the MASCC COG-IMPACT). Methods: A multistep mixed-methods measurement development and validation approach was taken with a strong emphasis on co-design. Qualitative interviews were conducted with cancer survivors (n = 32) and oncology health professionals (n = 19), followed by a modified Delphi survey with oncology health professionals (n = 29). Cognitive interviews with cancer survivors (n = 22) over two rounds were then conducted to finalise the penultimate version of the unmet needs assessment tool for CRCI. Four-hundred and ninety-one (n = 491) cancer survivors then completed the MASCC COG-IMPACT and other established measures to inform structural, reliability, validity, acceptability, appropriateness, and feasibility analyses. Results: The final MASCC COG-IMPACT is a 55-item and eight subscale tool including two indices: “difficulties” and “unmet needs”. The MASCC COG-IMPACT was found to have strong structural validity, convergent validity, discriminant validity, internal consistency, and test–retest reliability. The MASCC COG-IMPACT was also found to be highly acceptable, appropriate, and feasible. Conclusion: The MASCC COG-IMPACT may facilitate optimal care and referral in line with a cancer survivor’s CRCI-related difficulties and unmet needs. The MASCC COG-IMPACT may also be used to explore factors and contributors to CRCI-related difficulties and unmet needs. Overall, the MASCC COG-IMPACT is a highly reliable and valid tool for the assessment of CRCI-related difficulties and unmet needs in both clinical and research settings. The MASCC COG-IMPACT and supporting materials can be accessed on the MASCC webpage or via the MASCC COG-IMPACT Open Science Framework webpage (https://osf.io/5zc3a/).
DOI
10.1007/s00520-025-09149-7
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Haywood, D., Chan, A., Chan, R. J., Baughman, F. D., Dauer, E., Dhillon, H. M., ... & Hart, N. H. (2025). The MASCC COG-IMPACT: An unmet needs assessment for cancer-related cognitive impairment impact developed by the Multinational Association of Supportive Care in Cancer. Supportive Care in Cancer, 33. https://doi.org/10.1007/s00520-025-09149-7