Author Identifier

Liang Wang: https://orcid.org/0000-0001-5339-7484

Document Type

Journal Article

Publication Title

International Journal of Infectious Diseases

Volume

154

PubMed ID

40096882

Publisher

Elsevier

School

Centre for Precision Health / School of Medical and Health Sciences

Publication Unique Identifier

10.1016/j.ijid.2025.107890

Funders

Research Foundation for Advanced Talents of Guangdong Provincial People's Hospital (KY012023293, KJ012021097) / Guangdong Basic and Applied Basic Research Foundation (2022A1515220023) / Funding for Marshall Laboratory of Biomedical Engineering, Shenzhen University (86122-000001) / National Natural Science Foundation of China (82272423, 82072380)

Comments

Wang, L., Li, Z. K., Lai, J. X., Si, Y. T., Chen, J., Chua, E. G., ... & Gu, B. (2025). Risk factors associated with Helicobacter pylori infection in the urban population of China: A nationwide, multi-center, cross-sectional study. International Journal of Infectious Diseases, 154, 107890. https://doi.org/10.1016/j.ijid.2025.107890

Abstract

Objectives: To assess the risk factors associated with Helicobacter pylori infection in the urban Chinese population. Methods: The study was conducted from March to November 2023, including 12,902 urban participants aged 18-60 years across 52 cities distributed over 26 provinces in China. Risk factors included socioeconomic status, lifestyles, and public understanding. Univariate and multivariate logistic regression analysis was used to calculate corrected odds ratios (ORs) and 95% confidence intervals (CIs). Results: According to multivariate logistic regression, risk factors associated with significantly higher H. pylori infection rates included residency in developing (OR 1.27, 95% CI 1.13-1.43) and undeveloped cities (OR 1.15, 95% CI 1.02-1.29), obesity (OR 1.37, 95% CI 1.05-1.78), alcohol consumption (OR 1.16, 95% CI 1.05-1.29), tea consumption (OR 1.11, 95% CI 1.01-1.21), and soft drink consumption (OR 1.24, 95% CI 1.09-1.40). Conversely, individuals with moderate awareness (OR 0.79, 95% CI 0.71-0.88) and high awareness (OR 0.57, 95% CI 0.48-0.69) of H. pylori had lower infection rates. Conclusion: Our findings highlight the importance of promoting a healthy lifestyle and improving the understanding of H. pylori in reducing the infection rate of the bacterial pathogen in the urban Chinese population.

DOI

10.1016/j.ijid.2025.107890

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Download

Share

 
COinS