Author Identifier

Evalotte Mörelius: https://orcid.org/0000-0002-3256-5407

Document Type

Journal Article

Publication Title

Acta Paediatrica International Journal of Paediatrics

Publisher

Wiley

School

School of Nursing and Midwifery

Comments

Thornberg, U. B., Koch, F., Helmer, C. S., Tell, J., Nyberg, E., Abrahamsson, T., & Mörelius, E. (2025). Moderate‐to‐late preterm infants benefit from the early collaborative intervention: Primary outcomes of an RCT. Acta Paediatrica. Advance online publication. https://doi.org/10.1111/apa.70173

Abstract

Aim: This study aimed to determine the longitudinal impact of the EArly Collaborative Intervention (EACI), a three-session early intervention designed to enhance parent-infant interaction, on the developmental outcomes of preterm infants born between 30 + 0 and 35 + 6 weeks of gestation. Methods: This randomised controlled blinded study recruited families in two neonatal intensive care units in Sweden. In this one-year follow-up, 87 infants (standard care = 37, standard care with EACI = 50) were included in the intention-to-treat analysis. The primary study outcomes were cognition, receptive and expressive communication, and fine and gross motor development measured with the Bayley-III. Results: At one year of age (mean age 13.1 months SD = 0.64), there was a statistically significant effect in the intention-to-treat analysis on receptive communication F(1, 85) = 4.61, p = 0.035, η2 = 0.051. No statistically significant effects were found on the other Bayley-III outcome measures. There were no significant differences between the groups regarding gestational age, birth weight, gender, parents' education, or age at assessment. Conclusion: This new intervention indicates a small positive effect on moderate-to-late preterm infants' communication ability at one year of age. Though the attrition rate was relatively large, results are encouraging since clinical interventions supporting moderate-to-late preterm infants and parents are lacking. Trial Registration: ClinicalTrials.gov: NCT02034617.

DOI

10.1111/apa.70173

Creative Commons License

Creative Commons Attribution-Noncommercial 4.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial 4.0 License

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Link to publisher version (DOI)

10.1111/apa.70173