Author Identifier (ORCID)
Nai Chien Huan: https://orcid.org/0000-0002-2671-4189
Abstract
Pulmonary aspergilloma can cause life-threatening haemoptysis. Surgical resection and/or bronchial artery embolization (BAE) are established treatment modalities, but both can be risky in frail patients with comorbidities. Spontaneous regression of aspergilloma with antifungal agents alone is rare. We report an elderly gentleman with a background history of treated pulmonary tuberculosis, who presented with haemoptysis due to a large left upper lobe aspergilloma. He declined surgery and BAE due to perceived risks. Oral voriconazole and later isavuconazole were prescribed, which led to clinical improvement and significant reduction in the size of the aspergilloma over 6 months. Antifungal agents might be a viable therapeutic option for aspergilloma patients unsuitable or who declined more invasive procedures. Further studies are needed to validate the efficacy and safety of this approach.
Document Type
Journal Article
Date of Publication
8-1-2025
Volume
13
Issue
8
Publication Title
Respirology Case Reports
Publisher
Wiley
School
School of Medical and Health Sciences
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Chong, A. R., Ng, K. L., Huan, N., Aminudin, N. H. M., Rahaizat, R. N. a. R., & Nordin, K. M. (2025). Successful treatment of aspergilloma with antifungal alone: A case of conservative management. Respirology Case Reports, 13(8). https://doi.org/10.1002/rcr2.70334