Author Identifier (ORCID)
Natasya Raja Azlan: https://orcid.org/0009-0007-1838-8559
Debbie Massey: https://orcid.org/0000-0002-0466-1960
Lesley Andrew: https://orcid.org/0000-0003-0344-4611
Amanda Towell-Barnard: https://orcid.org/0000-0002-2475-7724
Seng Giap Marcus Ang: https://orcid.org/0000-0002-2617-6261
Carol Crevacore: https://orcid.org/0000-0003-4008-1418
Martina Costello: https://orcid.org/0000-0003-2280-3368
Aaron Alejandro: https://orcid.org/0000-0001-5604-6567
Weiting Liu: https://orcid.org/0000-0001-6936-8872
Naila Zaman: https://orcid.org/0009-0004-1054-8667
Abstract
Aims: To systematically summarise evidence related to the use of non-sterile gloves when preparing and administering intravenous antimicrobials. Design: Scoping review. Methods: A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for scoping review guidelines (2018). Five databases and grey literature were included in the search. Literature published between 2009 and 2024 was included. Data Sources: Five databases (Medline, CINAHL, EMBASE, Scopus and Web of Science) and the grey literature were searched in February 2024. Results: Three studies were included; however, none directly addressed correct non-sterile glove use during intravenous antimicrobial preparation or administration in clinical practice. Conclusion: We found no evidence to support the use of non-sterile gloves in intravenous antimicrobial preparation. There is an urgent need for rigorous research to inform the development of clear guidelines on non-sterile glove use to underpin evidence-based decision-making in nursing and other health professional education, improve patient outcomes, reduce healthcare costs and promote environmental sustainability in healthcare. Implications: Inappropriate use of non-sterile gloves for preparing and administering intravenous antimicrobials hinders correct hand hygiene practices and increases healthcare-associated infections, healthcare costs and waste. Impact: A critical gap in the existing evidence was a key finding of this review, highlighting the urgency for evidence-based guidelines to improve patient safety outcomes, reduce healthcare costs and promote environmental sustainability in healthcare. Reporting Method: This scoping review adhered to the relevant EQUATOR guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) reporting checklist. Patient of Public Contribution: This study did not include patient or public involvement in its design, conduct or reporting. Trial and Protocol Registration: The protocol was registered on Open Science Framework (https://doi.org/10.17605/OSF.IO/QY4J2).
Document Type
Journal Article
Date of Publication
1-1-2025
Publication Title
Journal of Advanced Nursing
Publisher
Wiley
School
School of Nursing and Midwifery
RAS ID
84232
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Azlan, N. R., Massey, D., Andrew, L., Towell‐Barnard, A., Ang, S. G. M., Crevacore, C., Costello, M., Alejandro, A., Liu, W., Zaman, N., & Zimmerman, P. (2025). Time to hang up the gloves: A scoping review of evidence on non‐sterile glove use during intravenous antimicrobial preparation and administration. Journal of Advanced Nursing. Advance online publication. https://doi.org/10.1111/jan.70197