Author Identifier (ORCID)
Jack Dalla Via: https://orcid.org/0000-0002-1815-0838
Simone Radavelli-Bagatini: https://orcid.org/0000-0001-6821-5217
Marc Sim: https://orcid.org/0000-0001-5166-0605
Abadi K. Gebre: https://orcid.org/0000-0002-1975-0085
Catherine P. Bondonno: https://orcid.org/0000-0001-8509-439X
Moira Sim: https://orcid.org/0000-0001-5962-6639
Jonathan M. Hodgson: https://orcid.org/0000-0001-6184-7764
Joshua R. Lewis: https://orcid.org/0000-0003-1003-8443
Abstract
Background: Provision of vascular imaging results has been investigated to prompt changes towards healthy lifestyle behaviours, but effects on body composition and muscle health are unknown. Aim: This secondary analysis of a 12-week parallel-group randomised controlled trial (RCT) aims to explore body composition and muscle health effects of providing healthy lifestyle education (Ed) with and without abdominal aortic calcification (AAC) results. Methods: A total of 240 Australian community-dwelling older men and women (mean ± SD age 68 ± 5 years; 58% female; 57.1% with evidence of AAC) were randomised to AAC + Ed (n = 121) or Control + Ed (n = 119). Linear mixed models were used to compare between-group changes in body composition (dual-energy X-ray absorptiometry), grip strength, and subjective physical function. Results: In total, 226 (94%) participants completed the trial. Provision of AAC results with lifestyle education provided no benefits to body composition, grip strength or physical function, compared to education alone. Exploratory analyses within the AAC + Ed group showed that those with evidence of AAC at baseline had greater declines in fat mass (net difference in change [95% CI] -0.6 [-1.0, -0.1] kg, p = 0.016) and visceral adipose tissue (-31 [-61, -1] g, p = 0.044) compared to those without evidence of AAC. Conclusions: Providing AAC results with healthy lifestyle education did not improve body composition or muscle health in older adults, compared to education alone. Provision of AAC results to those with evidence of AAC at baseline did improve total and visceral fat mass compared to those without evidence of AAC, but these findings require further investigation. Trial registration: Australian New Zealand Clinical Trial Registry (anzctr.org.au); registration number ACTRN12618001087246; registered 28/06/2018.
Keywords
Body composition, lifestyle, metabolic health, risk-reducing behaviours, vascular calcification
Document Type
Journal Article
Date of Publication
12-1-2026
Volume
38
Issue
1
PubMed ID
41670931
Publication Title
Aging Clinical and Experimental Research
Publisher
Springer
School
Nutrition and Health Innovation Research Institute / School of Medical and Health Sciences
Funders
MRFF Preventive and Public Health (APP1199751) / Royal Perth Hospital Research Foundation Fellowship (RPHRF CAF 00/21) / Western Australian Future Health Research and Innovation Fund (IG2021/5) / Lawrie Beilin Career Advancement Fellowship (CAF 127/2020) / National Heart Foundation (102817, 107323) / National Health and Medical Research Council
Grant Number
NHRMC Number : 1116973
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Via, J. D., Radavelli-Bagatini, S., Sim, M., Gebre, A. K., Bondonno, C. P., Zhu, K., Mullin, S., Schousboe, J. T., Woodman, R. J., Schlaich, M. P., Sim, M., Szulc, P., Kiel, D. P., Lim, W. H., Daly, R. M., Hodgson, J. M., & Lewis, J. R. (2026). Body composition and muscle health changes after providing vascular imaging results in older adults: Secondary analysis of a randomised controlled trial. Aging Clinical and Experimental Research, 38. https://doi.org/10.1007/s40520-026-03335-1