Rapid diagnosis of infectious diseases using microfluidic systems
Abstract
Infectious diseases remain the primary public health challenge in many countries. Every year, infectious diseases account for more than 13 million deaths around the world, and for 30% of the total burden of disease. Developing countries are especially challenged with infectious diseases. According to world health organization (WHO), 50% of the total deaths in developing countries are attributed to various infections, including respiratory tract infections, diarrheal diseases, human immunodeficiency virus (HIV), tuberculosis, and malaria. In the healthcare system, a diagnostic cycle consists of several time-consuming steps besides sample transportation, pre-and postanalytical phases, result transmission, and batching practices augmenting the turnaround time from disease interpretation to results (Figure 7.1) [1-3]. The downside of experience-based empiric therapy management involves the choice of inappropriate antibiotherapy or late initiation of treatment often resulting in treatment failure [4-7].
Document Type
Book Chapter
Date of Publication
2017
School
School of Medical and Health Sciences
Copyright
subscription content
Publisher
CRC Press / Taylor & Francis
Comments
Pandya, H. J., Draz, M. S., Warkiani, M. E., & Shafiee, H. (2017). Rapid diagnosis of infectious diseases using microfluidic systems. In F. Piraino & Š. Selimović (Eds.), Diagnostic Devices with Microfluidics (pp. 145-162). CRC Press. https://www.taylorfrancis.com/chapters/edit/10.1201/9781315154442-7/rapid-diagnosis-infectious-diseases-using-microfluidic-systems-hardik-jeetendra-pandya-mohamed-shehata-draz-majid-ebrahimi-warkiani-hadi-shafiee?context=ubx&refId=133c7953-78e4-4a47-8dd9-9f823e205e4c