Rapid diagnosis of infectious diseases using microfluidic systems

Document Type

Book Chapter

Publication Title

Diagnostic devices with microfluidics

First Page

145

Last Page

161

Publisher

CRC Press / Taylor & Francis

School

School of Medical and Health Sciences

Comments

Pandya, H. J., Draz, M. S., Warkiani, M. E., & Shafiee, H. (2017). Rapid diagnosis of infectious diseases using microfluidic systems. In F. Piraino & Š. Selimović (Eds.), Diagnostic Devices with Microfluidics (pp. 145-162). CRC Press. https://www.taylorfrancis.com/chapters/edit/10.1201/9781315154442-7/rapid-diagnosis-infectious-diseases-using-microfluidic-systems-hardik-jeetendra-pandya-mohamed-shehata-draz-majid-ebrahimi-warkiani-hadi-shafiee?context=ubx&refId=133c7953-78e4-4a47-8dd9-9f823e205e4c

Abstract

Infectious diseases remain the primary public health challenge in many countries. Every year, infectious diseases account for more than 13 million deaths around the world, and for 30% of the total burden of disease. Developing countries are especially challenged with infectious diseases. According to world health organization (WHO), 50% of the total deaths in developing countries are attributed to various infections, including respiratory tract infections, diarrheal diseases, human immunodeficiency virus (HIV), tuberculosis, and malaria. In the healthcare system, a diagnostic cycle consists of several time-consuming steps besides sample transportation, pre-and postanalytical phases, result transmission, and batching practices augmenting the turnaround time from disease interpretation to results (Figure 7.1) [1-3]. The downside of experience-based empiric therapy management involves the choice of inappropriate antibiotherapy or late initiation of treatment often resulting in treatment failure [4-7].

DOI

10.1201/9781315154442

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