Alzheimer's Disease: Toward a quantitative biological approach in describing its natural history and underlying mechanisms
Document Type
Book Chapter
Publication Title
The Molecular and Cellular Basis of Neurodegenerative Diseases
Publisher
Elsevier Inc
School
School of Medical and Health Sciences
RAS ID
27447
Abstract
Alzheimer’s disease remains a major therapeutic challenge despite a massive research effort over the past two decades. Applying quantitative mechanistic approaches to understanding the quantities and rates of Aβ amyloid production, accumulation and clearance may provide novel and more rigorous insights into developing rational therapeutic strategies.
DOI
10.1016/B978-0-12-811304-2.00003-1
Access Rights
subscription content
Comments
Masters, C. L., Gu, B., Laws, S., Lim, Y. Y., Roberts, B., Villemagne, V. L., & Beyreuther, K. (2018). Alzheimer’s Disease: Toward a quantitative biological approach in describing its natural history and underlying mechanisms. In M. S. Wolfe (Ed.), The Molecular and Cellular Basis of Neurodegenerative Diseases (pp. 57-79). Elsevier. https://doi.org/10.1016/B978-0-12-811304-2.00003-1