Alzheimer's Disease: Toward a quantitative biological approach in describing its natural history and underlying mechanisms

Abstract

Alzheimer’s disease remains a major therapeutic challenge despite a massive research effort over the past two decades. Applying quantitative mechanistic approaches to understanding the quantities and rates of Aβ amyloid production, accumulation and clearance may provide novel and more rigorous insights into developing rational therapeutic strategies.

RAS ID

27447

Document Type

Book Chapter

Date of Publication

2018

School

School of Medical and Health Sciences

Copyright

subscription content

Publisher

Elsevier Inc

Comments

Masters, C. L., Gu, B., Laws, S., Lim, Y. Y., Roberts, B., Villemagne, V. L., & Beyreuther, K. (2018). Alzheimer’s Disease: Toward a quantitative biological approach in describing its natural history and underlying mechanisms. In M. S. Wolfe (Ed.), The Molecular and Cellular Basis of Neurodegenerative Diseases (pp. 57-79). Elsevier. https://doi.org/10.1016/B978-0-12-811304-2.00003-1

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Link to publisher version (DOI)

10.1016/B978-0-12-811304-2.00003-1