High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions

Abstract

It is well established that different types of exercise can provide a powerful stimulus for mitochondrial biogenesis. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the efficacy of high-intensity exercise to promote mitochondrial biogenesis in humans. The purpose of this review is to examine current controversies in the field and to highlight some important methodological issues that need to be addressed to resolve existing conflicts.

Document Type

Journal Article

ISSN

1548-9221

Volume

34

Issue

1

PubMed ID

30540234

School

School of Medical and Health Sciences

RAS ID

31050

Copyright

subscription content

Publisher

The American Physiological Society

Comments

Bishop, D. J., Botella, J., Genders, A. J., Lee, M. J., Saner, N. J., Kuang, J., ... & Granata, C. (2019). High-intensity exercise and mitochondrial biogenesis: Current controversies and future research directions. Physiology, 34(1), 56-70.

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Link to publisher version (DOI)

10.1152/physiol.00038.2018