Towards quality assurance and quality control in untargeted metabolomics studies
Authors/Creators
Richard D. Beger
Warwick B. Dunn
Abbas Bandukwala
Bianca Bethan
David Broadhurst, Edith Cowan UniversityFollow
Clary B. Clish
Surendra Dasar
Leslie Derr
Annie Evans
Steve Fischer
Thomas Flynn
Thomas Hartung
David Herrington
Richard Higashi
Ping‑Ching Hsu
Christina Jones
Maureen Kachman
Helen Karuso
Gary Kruppa
Katrice Lippa
Padma Maruvada
Jonathan Mosley
Ioanna Ntai
Claire O’Donovan
Mary Playdon
Daniel Raftery
Daniel Shaughnessy
Amanda Souza
Timothy Spaeder
Barbara Spalholz
Fariba Tayyari
Baljit Ubhi
Mukesh Verma
Tilman Walk
Ian Wilson
Keren Witkin
Daniel W. Bearden
Krista A. Zanetti
Abstract
We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day ‘Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies’ held at the National Cancer Institute’s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.
RAS ID
29912
Document Type
Journal Article
Date of Publication
2019
ISSN
15733882
School
School of Science
Copyright
subscription content
Publisher
Springer New York LLC
Recommended Citation
Beger, R. D., Dunn, W. B., Bandukwala, A., Bethan, B., Broadhurst, D., Clish, C. B., Dasar, S., Derr, L., Evans, A., Fischer, S., Flynn, T., Hartung, T., Herrington, D., Higashi, R., Hsu, P., Jones, C., Kachman, M., Karuso, H., Kruppa, G., Lippa, K., Maruvada, P., Mosley, J., Ntai, I., O’Donovan, C., Playdon, M., Raftery, D., Shaughnessy, D., Souza, A., Spaeder, T., Spalholz, B., Tayyari, F., Ubhi, B., Verma, M., Walk, T., Wilson, I., Witkin, K., Bearden, D. W., & Zanetti, K. A. (2019). Towards quality assurance and quality control in untargeted metabolomics studies. DOI: https://doi.org/10.1007/s11306-018-1460-7
Comments
Beger, R.D., Dunn, W.B., Bandukwala, A. et al. (2019) Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics 15(4). Available here