Towards quality assurance and quality control in untargeted metabolomics studies

Abstract

We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day ‘Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies’ held at the National Cancer Institute’s Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.

Keywords

[RSTDPub], Quality assurance (QA), Quality control (QC), Community engagement, Test materials, Reporting metrics

Document Type

Journal Article

Date of Publication

2019

ISSN

15733882

Publication Title

Metabolomics

Publisher

Springer New York LLC

School

School of Science

RAS ID

29912

Comments

Beger, R.D., Dunn, W.B., Bandukwala, A. et al. (2019) Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics 15(4). Available here

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Link to publisher version (DOI)

10.1007/s11306-018-1460-7