Document Type
Journal Article
Publication Title
Environmental Health
ISSN
1476-069X
Volume
18
Issue
1
PubMed ID
31370900
Publisher
Springer
School
School of Medical and Health Sciences
RAS ID
31309
Funders
Program of the Natural Science Fund of China
Abstract
Background
Air pollution and cardiovascular disease are increasing problems in China. However, the short-term association between fine particulate matter (PM2.5) and cardiovascular disease (CVD) is not well documented. The purpose of this study is to estimate the short-term effects of PM2.5 on CVD admissions in Beijing, China.
Methods
In total, 460,938 electronic hospitalization summary reports for CVD between 2013 and 2017 were obtained. A generalized additive model using a quasi-Poisson distribution was used to investigate the association between exposure to PM2.5 and hospitalizations for total and cause-specific CVD, including coronary heart disease (CHD), atrial fibrillation (AF), and heart failure (HF) after controlling for the season, the day of the week, public holidays, and weather conditions. A stratified analysis was also conducted for age (18–64 and ≥ 65 years), sex and season.
Results
For every 10 μg/m3 increase in the PM2.5 concentration from the previous day to the current (lag 0–1) there was a significant increase in total CVD admissions (0.30, 95% CI: 0.20, 0.39%), with a strong association for older adults (aged ≥65 years), CHD (0.34, 95% CI: 0.22 to 0.45%) and AF (0.29, 95% CI, 0.03 to 0.55%). However, the observed increased risk was not statistically significant for HF hospitalizations. The associations in the single-pollutant models were robust to the inclusion of other pollutants in a two-pollutant model. No differences were found after stratification by sex and season.
Conclusions
Exposure to PM2.5 increased the risk of hospitalizations from CVD, especially for CHD, and appeared to have more influence in the elderly. Precautions and protective measures and efforts to reduce exposure to PM2.5 should be strengthened, especially for the elderly.
DOI
10.1186/s12940-019-0506-2
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Amsalu, E., Wang, T., Li, H., Liu, Y., Wang, A., Liu, X., ... Guo, X. (2019). Acute effects of fine particulate matter (PM 2.5) on hospital admissions for cardiovascular disease in Beijing, China: A time-series study. Environmental Health, 18(1).
Available here.