Influence of Ag alloying on the antibacterial properties, bio-corrosion resistance and biocompatibility of α-Nb5Si3 nanocrystalline coating
Authors
Jiang Xu
Shuang Peng
Bo Guo
Yantao Zhao
Tao Fu
Shuyun Jiang
Paul Munroe
Zong-Han Xie, Edith Cowan UniversityFollow
Hong Lu
Document Type
Journal Article
Publication Title
Applied Surface Science
Publisher
Elsevier
School
School of Engineering
RAS ID
34014
Abstract
To improve the corrosion resistance and impart the bioactivity and antibacterial functionalities to titanium alloys for biomedical applications, α-(Nb1-xAgx)5Si3 compounds, with three different Ag contents, were deposited on Ti–6Al–4V by double cathode glow discharge method. The new α-(Nb1-xAgx)5Si3 coatings, each about 16 μm in thickness, exhibited a compact uniform structure, composed of equiaxed nanocrystalline grains. Nanoindentation measurements revealed that Ag alloying reduced the hardness (H) and elastic modulus (E) values of the α-(Nb1-xAgx)5Si3 coatings. Compared to Ti–6Al–4V, the α-(Nb1-xAgx)5Si3 coatings exhibited improved corrosion resistance in Ringer's physiological solution, as well as newly added in-vitro bioactivity and antibacterial ability against both E. coli and S. aureus. A MTT assay experiment shows that the two α-(Nb1-xAgx)5Si3(x = 0 and 0.05) coatings were as non-cytotoxic as bare Ti-6Al-4V. However, the MC3T3-E1 osteoblast-like cell viability for the α-(Nb0.9Ag0.1)5Si3 coating was slightly reduced, suggesting that the proliferation of MC3T3-E1 osteoblast-like cell was affected to some degree by excess Ag added to α-Nb5Si3. Overall, the α-(Nb0.95Ag0.05)5Si3 coating provides an attractive combination of good bioactivity, high corrosion resistance and new antibacterial function, and thus demonstrates great potential for applications in orthopedic devices.
DOI
10.1016/j.apsusc.2019.144082
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Comments
Xu, J., Peng, S., Guo, B., Zhao, Y., Fu, T., Jiang, S., ... Lu, H. (2020). Influence of Ag alloying on the antibacterial properties, bio-corrosion resistance and biocompatibility of α-Nb5Si3 nanocrystalline coating. Applied Surface Science, 503, Article 144082. https://doi.org/10.1016/j.apsusc.2019.144082