Author Identifier
Lauren C. Blekkenhorst
https://orcid.org/0000-0003-1561-9052
Marc Sim
https://orcid.org/0000-0001-5166-0605
Simone Radavelli-Bagatini
https://orcid.org/0000-0001-6821-5217
Nicola P. Bondonno
https://orcid.org/0000-0001-5905-444X
Catherine P. Bondonno
https://orcid.org/0000-0001-8509-439X
Amanda Devine
https://orcid.org/0000-0001-6978-6249
Jonathan M. Hodgson
https://orcid.org/0000-0001-6184-7764
Joshua R. Lewis
Document Type
Journal Article
Publication Title
British Journal of Nutrition
Publisher
Cambridge University Press
School
School of Medical and Health Sciences
RAS ID
32411
Funders
Edith Cowan University - Open Access Support Scheme 2020
National Health and Medical Research Council of Australia
Grant Number
NHMRC Numbers : 1172987, 1159914, 1116973, 254627, 303169, 572604
Abstract
We have previously shown higher intake of cruciferous vegetables is inversely associated with carotid artery intima-media thickness. To further test the hypothesis that an increased consumption of cruciferous vegetables is associated with reduced indicators of structural vascular disease in other areas of the vascular tree, we aimed to investigate the cross-sectional association between cruciferous vegetable intake and extensive calcification in the abdominal aorta. Dietary intake was assessed, using a food frequency questionnaire, in 684 older women from the Calcium Intake Fracture Outcome Study. Cruciferous vegetables included cabbage, Brussels sprouts, cauliflower and broccoli. Abdominal aortic calcification (AAC) was scored using the Kauppila AAC24 scale on dual energy x-ray absorptiometry (DXA) lateral spine images, and was categorised as “not extensive” (0-5) or “extensive” (≥6). Mean age was 74.9 (SD 2.6) y, median cruciferous vegetable intake was 28.2 (IQR 15.0-44.7) g/d, and 128/684 (18.7%) women had extensive AAC scores. Those with higher intakes of cruciferous vegetables ( > 44.6 g/d) were associated with a 46% lower odds of having extensive AAC in comparison to those with lower intakes ( < 15.0 g/d) after adjustment for lifestyle, dietary and cardiovascular disease risk factors (ORQ4 vs Q1=0.54, 95%CI 0.30, 0.97, P=0.036). Total vegetable intake and each of the other vegetable types were not related to extensive AAC (P > 0.05 for all). This study strengthens the hypothesis that higher intake of cruciferous vegetables may protect against vascular calcification.
DOI
10.1017/S0007114520002706
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Comments
Blekkenhorst, L. C., Sim, M., Radavelli-Bagatini, S., Bondonno, N. P., Bondonno, C. P., Devine, A., ... & Hodgson, J. M. (2021). Cruciferous vegetable intake is inversely associated with extensive abdominal aortic calcification in elderly women: a cross-sectional study. British Journal of Nutrition, 125(3), 337-345.
https://doi.org/10.1017/S0007114520002706