Document Type

Journal Article

Publication Title

British Journal of Nutrition

Publisher

Cambridge University Press

School

School of Medical and Health Sciences

Funders

Edith Cowan University - Open Access Support Scheme

Comments

Blekkenhorst, L. C., Sim, M., Radavelli-Bagatini, S., Bondonno, N. P., Bondonno, C. P., Devine, A., ... & Hodgson, J. M. Cruciferous vegetable intake is inversely associated with extensive abdominal aortic calcification in elderly women: a cross-sectional study. British Journal of Nutrition, 1-19.

https://doi.org/10.1017/S0007114520002706

Abstract

We have previously shown higher intake of cruciferous vegetables is inversely associated with carotid artery intima-media thickness. To further test the hypothesis that an increased consumption of cruciferous vegetables is associated with reduced indicators of structural vascular disease in other areas of the vascular tree, we aimed to investigate the cross-sectional association between cruciferous vegetable intake and extensive calcification in the abdominal aorta. Dietary intake was assessed, using a food frequency questionnaire, in 684 older women from the Calcium Intake Fracture Outcome Study. Cruciferous vegetables included cabbage, Brussels sprouts, cauliflower and broccoli. Abdominal aortic calcification (AAC) was scored using the Kauppila AAC24 scale on dual energy x-ray absorptiometry (DXA) lateral spine images, and was categorised as “not extensive” (0-5) or “extensive” (≥6). Mean age was 74.9 (SD 2.6) y, median cruciferous vegetable intake was 28.2 (IQR 15.0-44.7) g/d, and 128/684 (18.7%) women had extensive AAC scores. Those with higher intakes of cruciferous vegetables ( > 44.6 g/d) were associated with a 46% lower odds of having extensive AAC in comparison to those with lower intakes ( < 15.0 g/d) after adjustment for lifestyle, dietary and cardiovascular disease risk factors (ORQ4 vs Q1=0.54, 95%CI 0.30, 0.97, P=0.036). Total vegetable intake and each of the other vegetable types were not related to extensive AAC (P > 0.05 for all). This study strengthens the hypothesis that higher intake of cruciferous vegetables may protect against vascular calcification.

DOI

10.1017/S0007114520002706

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Share

 
COinS