World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

Authors/Creators

• Miia Kivipelto
• Francesca Mangialasche
• Heather M. Snyder
• Ricardo Allegri
• Sandrine Andrieu
• Hidenori Arai
• Laura Baker
• Sylvie Belleville
• Henry Brodaty
• Sonia M. Brucki
• Ismael Calandri
• Paulo Caramelli
• Christopher Chen
• Howard Chertkow
• Effie Chew
• Seong H. Choi
• Neerja Chowdhary
• Lucía Crivelli
• Rafael De La Torre
• Yifeng Du
• Tarun Dua
• Mark Espeland
• Howard H. Feldman
• Maris Hartmanis
• Tobias Hartmann
• Megan Heffernan
• Christiani J. Henry
• Chang H. Hong
• Krister Hakansson
• Takeshi Iwatsubo
• Jee H. Jeong
• Gustavo Jimenez-Maggiora
• Edward H. Khoo
• Lenore J. Launer
• Jenni Lehtisalo
• Francisco Lopera
• Pablo Martinez-Lage
• Ralph Martins, Edith Cowan UniversityFollow
• Lefkos Middleton
• Jose L. Molinuevo
• Manuel Montero-Odasso
• So Y. Moon
• Kristal Morales-Perez
• Ricardo Nitrini
• Haakon B. Nygaard
• Yoo K. Park
• Markku Peltonen
• Chengxuan Qiu
• Yakeel T. Quiroz
• Rema Raman
• Naren Rao
• Vijayalakshmi Ravindranath
• Anna Rosenberg
• Takashi Sakurai
• Rosa M. Salinas
• Philip Scheltens
• Gustavo Sevlever
• Hilkka Soininen
• Ana L. Sosa
• Claudia K. Suemoto
• Mikel Tainta-Cuezva
• Lina Velilla
• Yongxiang Wang
• Rachel Whitmer
• Xin Xu
• Lisa J. Bain
• Alina Solomon
• Tiia Ngandu
• Maria C. Carrillo

Abstract

© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk reduction and prevention. WW-FINGERS aims to adapt, test, and optimize the FINGER model to reduce risk across the spectrum of cognitive decline—from at-risk asymptomatic states to early symptomatic stages—in different geographical, cultural, and economic settings. WW-FINGERS aims to harmonize and adapt multidomain interventions across various countries and settings, to facilitate data sharing and analysis across studies, and to promote international joint initiatives to identify globally implementable and effective preventive strategies.

Keywords

Alzheimer's disease, cognitive impairment, dementia, lifestyle, multidomain intervention, prevention, randomized controlled trial, World-Wide FINGERS

Document Type

Journal Article

Date of Publication

7-1-2020

ISSN

15525260

Volume

16

Issue

7

PubMed ID

32627328

Publication Title

Alzheimer's and Dementia

Publisher

Wiley

School

School of Medical and Health Sciences

RAS ID

35203

Creative Commons License

This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Comments

Kivipelto, M., Mangialasche, F., Snyder, H. M., Allegri, R., Andrieu, S., Arai, H., ... & Carrillo, M.C. (2020). World‐Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimer's & Dementia, 16(7), 1078-1094. https://doi.org/10.1002/alz.12123

First Page

1078

Last Page

1094