Authors/Creators
Haibin Li
Changwei Li
Anxin Wang
Yanling Qi
Wei Feng
Chengbei Hou
Lixin Tao
Xiangtong Liu
Xia Li
Wei Wang, Edith Cowan UniversityFollow
Deqiang Zheng
Xiuhua Guo
Abstract
BACKGROUND: Associations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study. METHODS: The China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 years from 2011 to 2016. Cognitive aging trajectories over time were analyzed using group-based trajectory modeling, and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odds ratios (OR) and 95% confidence intervals (CI) were reported. RESULTS: Among 8204 participants aged 50-75 years at baseline, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: "persistently low trajectory" (n = 1550, 18.9%), "persistently moderate trajectory" (n = 3194, 38.9%), and "persistently high trajectory" (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms, and health conditions, more frequent intellectual activities (OR 0.54, 95% CI 0.38-0.77) and social activities (OR 0.79, 95% CI 0.65-0.95) were both associated with a lower likelihood of being in the "persistently low trajectory" for global cognitive function. CONCLUSIONS: These findings suggested that more frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.
RAS ID
35293
Document Type
Journal Article
Date of Publication
9-25-2020
Volume
12
Issue
1
Funding Information
National Natural Science Foundation of China
PubMed ID
32977839
School
School of Medical and Health Sciences
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Publisher
Springer Nature
Recommended Citation
Li, H., Li, C., Wang, A., Qi, Y., Feng, W., Hou, C., Tao, L., Liu, X., Li, X., Wang, W., Zheng, D., & Guo, X. (2020). Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: A nationally representative cohort study. DOI: https://doi.org/10.1186/s13195-020-00691-6
Comments
Li, H., Li, C., Wang, A., Qi, Y., Feng, W., Hou, C., ... & Guo, X. (2020). Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study. Alzheimer's Research & Therapy, 12, article 115. https://doi.org/10.1186/s13195-020-00691-6