Effect of multidisciplinary rehabilitation on sleep outcomes in individuals with preclinical Huntington disease: An exploratory study

Abstract

Dear Editor Sleep disturbances are an early feature of Huntington disease (HD), which worsen as the disease progresses. Studies have documented increased sleep fragmentation, decreased rapid eye-movement (REM) sleep, reduced sleep efficiency, insomnia and an increase in periodic leg movements (PLMs) in individuals with HD [1], [2]. Disturbances in sleep are thought to exacerbate cognitive impairments and may hasten subcortical neurodegeneration [3], [4]. Hence, management of sleep disturbances in individuals with HD is imperative.

Document Type

Letter to the Editor

Date of Publication

2020

Volume

63

Issue

6

Funding Information

Lotterywest

PubMed ID

31778841

School

School of Medical and Health Sciences

Copyright

free_to_read

Publisher

Elsevier

Comments

Bartlett, D. M., Poudel, G., Maddison, K. J., Lampit, A., Dann, L., Eastwood, P. R., ... Cruickshank, T. M. (2020). Effect of multidisciplinary rehabilitation on sleep outcomes in individuals with preclinical Huntington disease: An exploratory study [Letter to the editor]. Annals of Physical and Rehabilitation Medicine, 63(6), 570-573. https://doi.org/10.1016/j.rehab.2019.11.003

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Link to publisher version (DOI)

10.1016/j.rehab.2019.11.003